<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>144</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001252243</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <issuerInfo>
      <issuerCik>0001493594</issuerCik>
      <issuerName>MACOM Technology Solutions Holdings, Inc.</issuerName>
      <secFileNumber>001-35451</secFileNumber>
      <issuerAddress>
        <com:street1>100 CHELMSFORD STREET</com:street1>
        <com:city>LOWELL</com:city>
        <com:stateOrCountry>MA</com:stateOrCountry>
        <com:zipCode>01851</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>(978) 656-2500</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>OCAMPO SUSAN</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>10% Stockholder</relationshipToIssuer>
      </relationshipsToIssuer>
    </issuerInfo>
    <securitiesInformation>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>The Charles Schwab Corporation</name>
        <address>
          <com:street1>3000 Schwab Way</com:street1>
          <com:city>Westlake</com:city>
          <com:stateOrCountry>TX</com:stateOrCountry>
          <com:zipCode>76262</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>150000</noOfUnitsSold>
      <aggregateMarketValue>19449000.00</aggregateMarketValue>
      <noOfUnitsOutstanding>74471281</noOfUnitsOutstanding>
      <approxSaleDate>09/18/2025</approxSaleDate>
      <securitiesExchangeName>NASDAQ</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <acquiredDate>06/30/2009</acquiredDate>
      <natureOfAcquisitionTransaction>Founder Shares</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>150000</amountOfSecuritiesAcquired>
      <paymentDate>06/03/2009</paymentDate>
      <natureOfPayment>N/A</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>SUSAN OCAMPO</name>
        <address>
          <com:street1>100 CHELMSFORD STREET</com:street1>
          <com:city>LOWELL</com:city>
          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>01851</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <saleDate>09/05/2025</saleDate>
      <amountOfSecuritiesSold>113275</amountOfSecuritiesSold>
      <grossProceeds>14885388.00</grossProceeds>
    </securitiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>SUSAN OCAMPO</name>
        <address>
          <com:street1>100 CHELMSFORD STREET</com:street1>
          <com:city>LOWELL</com:city>
          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>01851</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <saleDate>09/08/2025</saleDate>
      <amountOfSecuritiesSold>3195</amountOfSecuritiesSold>
      <grossProceeds>421918.00</grossProceeds>
    </securitiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>SUSAN OCAMPO</name>
        <address>
          <com:street1>100 CHELMSFORD STREET</com:street1>
          <com:city>LOWELL</com:city>
          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>01851</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <saleDate>09/09/2025</saleDate>
      <amountOfSecuritiesSold>45986</amountOfSecuritiesSold>
      <grossProceeds>6029536.00</grossProceeds>
    </securitiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>SUSAN OCAMPO</name>
        <address>
          <com:street1>100 CHELMSFORD STREET</com:street1>
          <com:city>LOWELL</com:city>
          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>01851</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <saleDate>09/10/2025</saleDate>
      <amountOfSecuritiesSold>50361</amountOfSecuritiesSold>
      <grossProceeds>6679719.00</grossProceeds>
    </securitiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>SUSAN OCAMPO</name>
        <address>
          <com:street1>100 CHELMSFORD STREET</com:street1>
          <com:city>LOWELL</com:city>
          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>01851</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <saleDate>09/11/2025</saleDate>
      <amountOfSecuritiesSold>80891</amountOfSecuritiesSold>
      <grossProceeds>10716701.00</grossProceeds>
    </securitiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>SUSAN OCAMPO</name>
        <address>
          <com:street1>100 CHELMSFORD STREET</com:street1>
          <com:city>LOWELL</com:city>
          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>01851</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <saleDate>09/12/2025</saleDate>
      <amountOfSecuritiesSold>89868</amountOfSecuritiesSold>
      <grossProceeds>11940024.00</grossProceeds>
    </securitiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>SUSAN OCAMPO</name>
        <address>
          <com:street1>100 CHELMSFORD STREET</com:street1>
          <com:city>LOWELL</com:city>
          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>01851</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <saleDate>09/15/2025</saleDate>
      <amountOfSecuritiesSold>150424</amountOfSecuritiesSold>
      <grossProceeds>19920486.00</grossProceeds>
    </securitiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>SUSAN OCAMPO</name>
        <address>
          <com:street1>100 CHELMSFORD STREET</com:street1>
          <com:city>LOWELL</com:city>
          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>01851</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <saleDate>09/17/2025</saleDate>
      <amountOfSecuritiesSold>62435</amountOfSecuritiesSold>
      <grossProceeds>8305195.00</grossProceeds>
    </securitiesSoldInPast3Months>
    <remarks>Filing encompasses 3 Trust accounts in which Susan Ocampo is the TTEE

4 WK average volume
Wk 1 2,790,200
Wk 2 4,351,000
Wk 3 3,033,600
Wk 4 4,047,400
Total = 14,222,200 / 4 = 3,555,550 shares per week average - total 746,435  sold so far
</remarks>
    <noticeSignature>
      <noticeDate>09/18/2025</noticeDate>
      <signature>Susan O'Campo</signature>
    </noticeSignature>
  </formData>
</edgarSubmission>
