Balance Sheet Details - Property and Equipment, Net (Detail) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Property, Plant and Equipment [Line Items]
Property and equipment, gross	$ 8,151	$ 8,645
Less: accumulated depreciation and amortization	(6,380)	(5,879)
Total	1,771	2,766
Laboratory Equipment [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	4,252	4,265
Manufacturing Equipment [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	82	1,075
Computer Equipment and Software [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	1,488	989
Leasehold Improvements [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	822	768
Office Furniture [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	$ 1,507	$ 1,548

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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