The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
89BIO INC COM 282559103   58,478,437 7,478,061 SH   SOLE   7,478,061 0 0
ACADIA PHARMACEUTICALS INC COM 004225108   159,745,943 8,705,501 SH   SOLE   8,705,501 0 0
ACELYRIN INC COM 00445A100   3,071,893 978,310 SH   SOLE   978,310 0 0
ADAGIO MED HLDGS INC COM 00534B100   219,829 209,361 SH   SOLE   209,361 0 0
AKERO THERAPEUTICS INC COM 00973Y108   190,840,276 6,859,823 SH   SOLE   6,859,823 0 0
ALKERMES PLC SHS G01767105   217,363,335 7,557,835 SH   SOLE   7,557,835 0 0
ALLURION TECHNOLOGIES INC COM SHS 02008G102   1,267,447 2,947,551 SH   SOLE   2,947,551 0 0
APOGEE THERAPEUTICS INC COM 03770N101   122,857,994 2,712,097 SH   SOLE   2,712,097 0 0
ARGENX SE SPONSORED ADR 04016X101   414,200,655 673,497 SH   SOLE   673,497 0 0
ARTIVA BIOTHERAPEUTICS INC COM 04317A107   1,500,348 148,844 SH   SOLE   148,844 0 0
ARVINAS INC COM 04335A105   63,918,684 3,334,308 SH   SOLE   3,334,308 0 0
AVIDITY BIOSCIENCES INC COM 05370A108   230,687,860 7,932,870 SH   SOLE   7,932,870 0 0
AXSOME THERAPEUTICS INC COM 05464T104   342,785,993 4,051,365 SH   SOLE   4,051,365 0 0
BIOAGE LABS INC COM 09077V100   4,552,984 786,353 SH   SOLE   786,353 0 0
BRUKER CORP COM 116794108   145,443,196 2,481,119 SH   SOLE   2,481,119 0 0
CARGO THERAPEUTICS INC COM 14179K101   59,480,467 4,124,859 SH   SOLE   4,124,859 0 0
CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100   837,500 50,000 SH   SOLE   50,000 0 0
CERIBELL INC COM 15678C102   3,882,000 150,000 SH   SOLE   150,000 0 0
CG ONCOLOGY INC COM 156944100   48,790,875 1,701,216 SH   SOLE   1,701,216 0 0
COMPASS PATHWAYS PLC SPONSORED ADS 20451W101   11,714,171 3,098,987 SH   SOLE   3,098,987 0 0
CORVUS PHARMACEUTICALS INC COM 221015100   14,335,213 2,679,479 SH   SOLE   2,679,479 0 0
CULLINAN THERAPEUTICS INC COM 230031106   20,778,593 1,705,960 SH   SOLE   1,705,960 0 0
CYTOKINETICS INC COM NEW 23282W605   128,003,272 2,721,158 SH   SOLE   2,721,158 0 0
DIANTHUS THERAPEUTICS INC COM 252828108   14,533,341 666,667 SH   SOLE   666,667 0 0
DYNE THERAPEUTICS INC COM 26818M108   122,951,182 5,218,641 SH   SOLE   5,218,641 0 0
ESSA PHARMA INC COM NEW 29668H708   1,992,274 1,113,002 SH   SOLE   1,113,002 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108   118,385,480 2,569,687 SH   SOLE   2,569,687 0 0
EXAGEN INC COM 30068X103   6,198,651 1,511,866 SH   SOLE   1,511,866 0 0
GH RESEARCH PLC ORDINARY SHARES G3855L106   23,289,903 3,327,129 SH   SOLE   3,327,129 0 0
GLOBUS MED INC CL A 379577208   80,394,120 972,000 SH   SOLE   972,000 0 0
IDEAYA BIOSCIENCES INC COM 45166A102   5,140,000 200,000 SH   SOLE   200,000 0 0
IMMATICS N.V SHS N44445109   46,503,239 6,540,540 SH   SOLE   6,540,540 0 0
IMMUNIC INC COM 4525EP101   4,567,717 4,567,717 SH   SOLE   4,567,717 0 0
IMMUNOCORE HLDGS PLC ADS 45258D105   143,659,041 4,869,798 SH   SOLE   4,869,798 0 0
IMMUNOVANT INC COM 45258J102   13,143,309 530,614 SH   SOLE   530,614 0 0
INSMED INC COM PAR $.01 457669307   208,125,084 3,014,558 SH   SOLE   3,014,558 0 0
LENZ THERAPEUTICS INC COM 52635N103   24,926,040 863,389 SH   SOLE   863,389 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105   615,191,998 1,993,687 SH   SOLE   1,993,687 0 0
MASIMO CORP COM 574795100   112,948,498 683,294 SH   SOLE   683,294 0 0
MERUS N V COM N5749R100   175,322,976 4,169,393 SH   SOLE   4,169,393 0 0
MILESTONE PHARMACEUTICALS IN COM 59935V107   5,914,401 2,506,102 SH   SOLE   2,506,102 0 0
NATERA INC COM 632307104   410,523,031 2,593,323 SH   SOLE   2,593,323 0 0
NEUROGENE INC COM 64135M105   30,866,852 1,350,256 SH   SOLE   1,350,256 0 0
ORCHESTRA BIOMED HLDGS INC COM 68572M106   32,824,648 8,206,162 SH   SOLE   8,206,162 0 0
ORUKA THERAPEUTICS INC COM 687604108   37,726,134 1,945,649 SH   SOLE   1,945,649 0 0
PENUMBRA INC COM 70975L107   204,814,626 862,450 SH   SOLE   862,450 0 0
PEPGEN INC COM 713317105   12,101,838 3,193,097 SH   SOLE   3,193,097 0 0
PERCEPTIVE CAP SOLUTIONS COR CL A ORD SHS G70077105   7,558,650 742,500 SH   SOLE   742,500 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102   212,243,837 5,498,545 SH   SOLE   5,498,545 0 0
PTC THERAPEUTICS INC COM 69366J200   333,725,753 7,393,127 SH   SOLE   7,393,127 0 0
RADNET INC COM 750491102   138,184,167 1,978,582 SH   SOLE   1,978,582 0 0
RAPT THERAPEUTICS INC COM 75382E109   18,587,120 11,764,000 SH   SOLE   11,764,000 0 0
REGENXBIO INC COM 75901B107   2,705,500 350,000 SH   SOLE   350,000 0 0
REPLIMUNE GROUP INC COM 76029N106   25,007,271 2,065,010 SH   SOLE   2,065,010 0 0
ROCKET PHARMACEUTICALS INC *W EXP 09/02/202 77313F114   12,005 350,000 SH   SOLE   350,000 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106   222,335,294 17,687,772 SH   SOLE   17,687,772 0 0
ROIVANT SCIENCES LTD SHS G76279101   17,204,050 1,454,273 SH   SOLE   1,454,273 0 0
SAGE THERAPEUTICS INC COM 78667J108   16,302,869 3,002,370 SH   SOLE   3,002,370 0 0
SPYRE THERAPEUTICS INC COM NEW 00773J202   84,320,067 3,621,996 SH   SOLE   3,621,996 0 0
STOKE THERAPEUTICS INC COM 86150R107   56,512,481 5,123,525 SH   SOLE   5,123,525 0 0
STRUCTURE THERAPEUTICS INC SPONSORED ADS 86366E106   3,390,000 125,000 SH   SOLE   125,000 0 0
STRYKER CORPORATION COM 863667101   212,509,071 590,221 SH   SOLE   590,221 0 0
TARSUS PHARMACEUTICALS INC COM 87650L103   179,207,718 3,236,549 SH   SOLE   3,236,549 0 0
TAYSHA GENE THERAPIES INC COM SHS 877619106   15,003,650 8,672,630 SH   SOLE   8,672,630 0 0
TOURMALINE BIO INC COM 89157D105   14,939,891 736,681 SH   SOLE   736,681 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108   82,793,844 1,968,002 SH   SOLE   1,968,002 0 0
UNIQURE NV SHS N90064101   15,958,018 903,625 SH   SOLE   903,625 0 0
UROGEN PHARMA LTD COM M96088105   40,840,556 3,834,794 SH   SOLE   3,834,794 0 0
VERONA PHARMA PLC SPONSORED ADS 925050106   84,568,122 1,821,019 SH   SOLE   1,821,019 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105   11,133,000 900,000 SH   SOLE   900,000 0 0
XENCOR INC COM 98401F105   55,218,251 2,402,883 SH   SOLE   2,402,883 0 0
ZAI LAB LTD ADR 98887Q104   65,713,827 2,509,119 SH   SOLE   2,509,119 0 0