The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
10X GENOMICS INC CL A COM 88025U109   86,735,258 1,549,951 SH   SOLE   1,549,951 0 0
89BIO INC COM 282559103   62,316,659 5,578,931 SH   SOLE   5,578,931 0 0
ACADIA PHARMACEUTICALS INC COM 004225108   352,348,682 11,253,551 SH   SOLE   11,253,551 0 0
ACELYRIN INC COM 00445A100   7,298,193 978,310 SH   SOLE   978,310 0 0
ADICET BIO INC COM 007002108   7,814,453 4,134,631 SH   SOLE   4,134,631 0 0
AKERO THERAPEUTICS INC COM 00973Y108   83,890,923 3,592,759 SH   SOLE   3,592,759 0 0
ALKERMES PLC SHS G01767105   108,228,248 3,901,523 SH   SOLE   3,901,523 0 0
ALLURION TECHNOLOGIES INC COM SHS 02008G102   12,931,824 3,457,707 SH   SOLE   3,457,707 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107   314,019,398 1,640,559 SH   SOLE   1,640,559 0 0
APOGEE THERAPEUTICS INC COM 03770N101   59,863,993 2,142,591 SH   SOLE   2,142,591 0 0
APYX MEDICAL CORPORATION COM 03837C106   2,688,023 1,025,963 SH   SOLE   1,025,963 0 0
ARGENX SE SPONSORED ADR 04016X101   253,820,994 667,195 SH   SOLE   667,195 0 0
ARVINAS INC COM 04335A105   173,426,960 4,213,483 SH   SOLE   4,213,483 0 0
ARYA SCIENCES ACQU CORP IV CL A G31659108   1,394,873 127,970 SH   SOLE   127,970 0 0
AVADEL PHARMACEUTICALS PLC SPONSORED ADR 05337M104   98,104,602 6,947,918 SH   SOLE   6,947,918 0 0
AVIDITY BIOSCIENCES INC COM 05370A108   60,542,590 6,689,789 SH   SOLE   6,689,789 0 0
AXSOME THERAPEUTICS INC COM 05464T104   357,326,946 4,489,596 SH   SOLE   4,489,596 0 0
BRUKER CORP COM 116794108   245,724,101 3,344,095 SH   SOLE   3,344,095 0 0
CARGO THERAPEUTICS INC COM 14179K101   119,820,511 5,175,832 SH   SOLE   5,175,832 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202   137,350,552 3,463,201 SH   SOLE   3,463,201 0 0
CUTERA INC COM 232109108   6,406,987 1,817,585 SH   SOLE   1,817,585 0 0
CYTOKINETICS INC COM NEW 23282W605   210,818,929 2,525,080 SH   SOLE   2,525,080 0 0
DANAHER CORPORATION COM 235851102   27,433,223 118,584 SH   SOLE   118,584 0 0
ESSA PHARMA INC COM NEW 29668H708   15,171,169 2,298,662 SH   SOLE   2,298,662 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108   64,573,233 2,494,138 SH   SOLE   2,494,138 0 0
EXAGEN INC COM 30068X103   2,994,158 1,504,602 SH   SOLE   1,504,602 0 0
FULCRUM THERAPEUTICS INC COM 359616109   36,922,203 5,469,956 SH   SOLE   5,469,956 0 0
GH RESEARCH PLC ORDINARY SHARES G3855L106   19,297,348 3,327,129 SH   SOLE   3,327,129 0 0
GUARDANT HEALTH INC COM 40131M109   13,335,028 492,977 SH   SOLE   492,977 0 0
IMMATICS N.V SHS N44445109   15,636,113 1,484,911 SH   SOLE   1,484,911 0 0
IMMUNIC INC COM 4525EP101   6,502,883 4,335,255 SH   SOLE   4,335,255 0 0
IMMUNOCORE HLDGS PLC ADS 45258D105   416,505,160 6,096,387 SH   SOLE   6,096,387 0 0
INSMED INC COM PAR $.01 457669307   57,799,697 1,865,108 SH   SOLE   1,865,108 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105   188,618,894 815,191 SH   SOLE   815,191 0 0
MASIMO CORP COM 574795100   171,407,904 1,462,400 SH   SOLE   1,462,400 0 0
MERUS N V COM N5749R100   65,274,688 2,373,625 SH   SOLE   2,373,625 0 0
MILESTONE PHARMACEUTICALS IN COM 59935V107   5,437,690 3,256,102 SH   SOLE   3,256,102 0 0
MIRATI THERAPEUTICS INC COM 60468T105   397,650,198 6,768,514 SH   SOLE   6,768,514 0 0
NATERA INC COM 632307104   162,445,753 2,593,323 SH   SOLE   2,593,323 0 0
ORCHESTRA BIOMED HLDGS INC COM 68572M106   51,316,443 5,620,640 SH   SOLE   5,620,640 0 0
PENUMBRA INC COM 70975L107   166,686,503 662,664 SH   SOLE   662,664 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102   121,884,736 5,315,514 SH   SOLE   5,315,514 0 0
PTC THERAPEUTICS INC COM 69366J200   204,604,613 7,423,970 SH   SOLE   7,423,970 0 0
RADNET INC COM 750491102   23,073,442 663,602 SH   SOLE   663,602 0 0
ROCKET PHARMACEUTICALS INC *W EXP 09/02/202 77313F114   171,500 350,000 SH   SOLE   350,000 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106   530,102,527 17,687,772 SH   SOLE   17,687,772 0 0
ROIVANT SCIENCES LTD SHS G76279101   16,331,486 1,454,273 SH   SOLE   1,454,273 0 0
SAB BIOTHERAPEUTICS INC COM 78397T103   6,310,069 9,178,282 SH   SOLE   9,178,282 0 0
SAGE THERAPEUTICS INC COM 78667J108   112,619,402 5,197,019 SH   SOLE   5,197,019 0 0
SHOCKWAVE MED INC COM 82489T104   12,397,834 65,060 SH   SOLE   65,060 0 0
SIENTRA INC COM 82621J204   49,420 81,016 SH   SOLE   81,016 0 0
SIGHT SCIENCES INC COM 82657M105   850,399 164,806 SH   SOLE   164,806 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107   22,812,500 625,000 SH   SOLE   625,000 0 0
SPYRE THERAPEUTICS INC COM NEW 00773J202   48,048,995 2,232,760 SH   SOLE   2,232,760 0 0
STOKE THERAPEUTICS INC COM 86150R107   21,729,297 4,131,045 SH   SOLE   4,131,045 0 0
TANGO THERAPEUTICS INC COM 87583X109   19,470,845 1,966,752 SH   SOLE   1,966,752 0 0
TARSUS PHARMACEUTICALS INC COM 87650L103   63,834,905 3,152,341 SH   SOLE   3,152,341 0 0
TAYSHA GENE THERAPIES INC COM SHS 877619106   29,900,937 16,893,185 SH   SOLE   16,893,185 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102   26,539,500 50,000 SH   SOLE   50,000 0 0
TOURMALINE BIO INC COM 89157D105   10,441,893 398,850 SH   SOLE   398,850 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108   329,340,453 6,887,086 SH   SOLE   6,887,086 0 0
UROGEN PHARMA LTD COM M96088105   25,902,120 1,726,808 SH   SOLE   1,726,808 0 0
VERICEL CORP COM 92346J108   114,407,594 3,212,794 SH   SOLE   3,212,794 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104   13,194,673 605,816 SH   SOLE   605,816 0 0