0001493152-24-006286.txt : 20240214 0001493152-24-006286.hdr.sgml : 20240214 20240214060531 ACCESSION NUMBER: 0001493152-24-006286 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20231231 FILED AS OF DATE: 20240214 DATE AS OF CHANGE: 20240214 EFFECTIVENESS DATE: 20240214 FILER: COMPANY DATA: COMPANY CONFORMED NAME: RTW INVESTMENTS, LP CENTRAL INDEX KEY: 0001493215 ORGANIZATION NAME: IRS NUMBER: 000000000 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-16670 FILM NUMBER: 24631859 BUSINESS ADDRESS: STREET 1: 40 10TH AVENUE STREET 2: 7TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10014 BUSINESS PHONE: 646-597-6980 MAIL ADDRESS: STREET 1: 40 10TH AVENUE STREET 2: 7TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10014 FORMER COMPANY: FORMER CONFORMED NAME: RTW INVESTMENTS, LLC DATE OF NAME CHANGE: 20100602 13F-HR 1 primary_doc.xml X0202 13F-HR LIVE false true false 0001493215 XXXXXXXX 12-31-2023 12-31-2023 false RTW INVESTMENTS, LP

40 10TH AVENUE 7Th FLOOR NEW YORK NY 10014

13F HOLDINGS REPORT 028-16670 000153232 801-78183 N Roderick Wong 646-597-6980 /s/ Roderick Wong New York NY 02-14-2024 0 64 6401901127 INFORMATION TABLE 2 infotable.xml 10X GENOMICS INC CL A COM 88025U109 86735258 1549951 SH SOLE 1549951 0 0 89BIO INC COM 282559103 62316659 5578931 SH SOLE 5578931 0 0 ACADIA PHARMACEUTICALS INC COM 004225108 352348682 11253551 SH SOLE 11253551 0 0 ACELYRIN INC COM 00445A100 7298193 978310 SH SOLE 978310 0 0 ADICET BIO INC COM 007002108 7814453 4134631 SH SOLE 4134631 0 0 AKERO THERAPEUTICS INC COM 00973Y108 83890923 3592759 SH SOLE 3592759 0 0 ALKERMES PLC SHS G01767105 108228248 3901523 SH SOLE 3901523 0 0 ALLURION TECHNOLOGIES INC COM SHS 02008G102 12931824 3457707 SH SOLE 3457707 0 0 ALNYLAM PHARMACEUTICALS INC COM 02043Q107 314019398 1640559 SH SOLE 1640559 0 0 APOGEE THERAPEUTICS INC COM 03770N101 59863993 2142591 SH SOLE 2142591 0 0 APYX MEDICAL CORPORATION COM 03837C106 2688023 1025963 SH SOLE 1025963 0 0 ARGENX SE SPONSORED ADR 04016X101 253820994 667195 SH SOLE 667195 0 0 ARVINAS INC COM 04335A105 173426960 4213483 SH SOLE 4213483 0 0 ARYA SCIENCES ACQU CORP IV CL A G31659108 1394873 127970 SH SOLE 127970 0 0 AVADEL PHARMACEUTICALS PLC SPONSORED ADR 05337M104 98104602 6947918 SH SOLE 6947918 0 0 AVIDITY BIOSCIENCES INC COM 05370A108 60542590 6689789 SH SOLE 6689789 0 0 AXSOME THERAPEUTICS INC COM 05464T104 357326946 4489596 SH SOLE 4489596 0 0 BRUKER CORP COM 116794108 245724101 3344095 SH SOLE 3344095 0 0 CARGO THERAPEUTICS INC COM 14179K101 119820511 5175832 SH SOLE 5175832 0 0 CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 137350552 3463201 SH SOLE 3463201 0 0 CUTERA INC COM 232109108 6406987 1817585 SH SOLE 1817585 0 0 CYTOKINETICS INC COM NEW 23282W605 210818929 2525080 SH SOLE 2525080 0 0 DANAHER CORPORATION COM 235851102 27433223 118584 SH SOLE 118584 0 0 ESSA PHARMA INC COM NEW 29668H708 15171169 2298662 SH SOLE 2298662 0 0 ESTABLISHMENT LABS HLDGS INC COM G31249108 64573233 2494138 SH SOLE 2494138 0 0 EXAGEN INC COM 30068X103 2994158 1504602 SH SOLE 1504602 0 0 FULCRUM THERAPEUTICS INC COM 359616109 36922203 5469956 SH SOLE 5469956 0 0 GH RESEARCH PLC ORDINARY SHARES G3855L106 19297348 3327129 SH SOLE 3327129 0 0 GUARDANT HEALTH INC COM 40131M109 13335028 492977 SH SOLE 492977 0 0 IMMATICS N.V SHS N44445109 15636113 1484911 SH SOLE 1484911 0 0 IMMUNIC INC COM 4525EP101 6502883 4335255 SH SOLE 4335255 0 0 IMMUNOCORE HLDGS PLC ADS 45258D105 416505160 6096387 SH SOLE 6096387 0 0 INSMED INC COM PAR $.01 457669307 57799697 1865108 SH SOLE 1865108 0 0 MADRIGAL PHARMACEUTICALS INC COM 558868105 188618894 815191 SH SOLE 815191 0 0 MASIMO CORP COM 574795100 171407904 1462400 SH SOLE 1462400 0 0 MERUS N V COM N5749R100 65274688 2373625 SH SOLE 2373625 0 0 MILESTONE PHARMACEUTICALS IN COM 59935V107 5437690 3256102 SH SOLE 3256102 0 0 MIRATI THERAPEUTICS INC COM 60468T105 397650198 6768514 SH SOLE 6768514 0 0 NATERA INC COM 632307104 162445753 2593323 SH SOLE 2593323 0 0 ORCHESTRA BIOMED HLDGS INC COM 68572M106 51316443 5620640 SH SOLE 5620640 0 0 PENUMBRA INC COM 70975L107 166686503 662664 SH SOLE 662664 0 0 PROTAGONIST THERAPEUTICS INC COM 74366E102 121884736 5315514 SH SOLE 5315514 0 0 PTC THERAPEUTICS INC COM 69366J200 204604613 7423970 SH SOLE 7423970 0 0 RADNET INC COM 750491102 23073442 663602 SH SOLE 663602 0 0 ROCKET PHARMACEUTICALS INC *W EXP 09/02/202 77313F114 171500 350000 SH SOLE 350000 0 0 ROCKET PHARMACEUTICALS INC COM 77313F106 530102527 17687772 SH SOLE 17687772 0 0 ROIVANT SCIENCES LTD SHS G76279101 16331486 1454273 SH SOLE 1454273 0 0 SAB BIOTHERAPEUTICS INC COM 78397T103 6310069 9178282 SH SOLE 9178282 0 0 SAGE THERAPEUTICS INC COM 78667J108 112619402 5197019 SH SOLE 5197019 0 0 SHOCKWAVE MED INC COM 82489T104 12397834 65060 SH SOLE 65060 0 0 SIENTRA INC COM 82621J204 49420 81016 SH SOLE 81016 0 0 SIGHT SCIENCES INC COM 82657M105 850399 164806 SH SOLE 164806 0 0 SPRINGWORKS THERAPEUTICS INC COM 85205L107 22812500 625000 SH SOLE 625000 0 0 SPYRE THERAPEUTICS INC COM NEW 00773J202 48048995 2232760 SH SOLE 2232760 0 0 STOKE THERAPEUTICS INC COM 86150R107 21729297 4131045 SH SOLE 4131045 0 0 TANGO THERAPEUTICS INC COM 87583X109 19470845 1966752 SH SOLE 1966752 0 0 TARSUS PHARMACEUTICALS INC COM 87650L103 63834905 3152341 SH SOLE 3152341 0 0 TAYSHA GENE THERAPIES INC COM SHS 877619106 29900937 16893185 SH SOLE 16893185 0 0 THERMO FISHER SCIENTIFIC INC COM 883556102 26539500 50000 SH SOLE 50000 0 0 TOURMALINE BIO INC COM 89157D105 10441893 398850 SH SOLE 398850 0 0 ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 329340453 6887086 SH SOLE 6887086 0 0 UROGEN PHARMA LTD COM M96088105 25902120 1726808 SH SOLE 1726808 0 0 VERICEL CORP COM 92346J108 114407594 3212794 SH SOLE 3212794 0 0 VIRIDIAN THERAPEUTICS INC COM 92790C104 13194673 605816 SH SOLE 605816 0 0