The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
10X GENOMICS INC CL A COM 88025U109   62,698,185 1,519,956 SH   SOLE   1,519,956 0 0
ACADIA PHARMACEUTICALS INC COM 004225108   241,255,031 11,576,537 SH   SOLE   11,576,537 0 0
ACELYRIN INC COM 00445A100   9,949,413 978,310 SH   SOLE   978,310 0 0
ADICET BIO INC COM 007002108   5,810,817 4,241,472 SH   SOLE   4,241,472 0 0
AKOYA BIOSCIENCES INC COM 00974H104   1,573,662 338,422 SH   SOLE   338,422 0 0
ALKERMES PLC SHS G01767105   24,902,935 889,073 SH   SOLE   889,073 0 0
ALLURION TECHNOLOGIES INC COM SHS 02008G102   14,868,140 3,457,707 SH   SOLE   3,457,707 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107   298,123,410 1,683,362 SH   SOLE   1,683,362 0 0
APOGEE THERAPEUTICS INC COM 03770N101   45,637,188 2,142,591 SH   SOLE   2,142,591 0 0
APYX MEDICAL CORPORATION COM 03837C106   5,687,021 1,777,194 SH   SOLE   1,777,194 0 0
ARGENX SE SPONSORED ADR 04016X101   249,352,278 507,195 SH   SOLE   507,195 0 0
ARYA SCIENCES ACQU CORP IV CL A G31659108   1,384,635 127,970 SH   SOLE   127,970 0 0
AVADEL PHARMACEUTICALS PLC SPONSORED ADR 05337M104   73,505,075 7,136,415 SH   SOLE   7,136,415 0 0
AVIDITY BIOSCIENCES INC COM 05370A108   42,680,854 6,689,789 SH   SOLE   6,689,789 0 0
AXONICS INC COM 05465P101   24,832,370 442,487 SH   SOLE   442,487 0 0
AXSOME THERAPEUTICS INC COM 05464T104   313,777,864 4,489,596 SH   SOLE   4,489,596 0 0
BRUKER CORP COM 116794108   210,680,097 3,381,703 SH   SOLE   3,381,703 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202   95,307,292 3,463,201 SH   SOLE   3,463,201 0 0
CUTERA INC COM 232109108   11,116,508 1,846,596 SH   SOLE   1,846,596 0 0
CYTOKINETICS INC COM NEW 23282W605   75,835,873 2,574,198 SH   SOLE   2,574,198 0 0
DERMTECH INC COM 24984K105   3,914,433 2,718,356 SH   SOLE   2,718,356 0 0
DESIGN THERAPEUTICS INC COM 25056L103   5,930,647 2,512,986 SH   SOLE   2,512,986 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108   122,387,352 2,494,138 SH   SOLE   2,494,138 0 0
EXAGEN INC COM 30068X103   3,611,685 1,492,432 SH   SOLE   1,492,432 0 0
FULCRUM THERAPEUTICS INC COM 359616109   25,835,490 5,818,804 SH   SOLE   5,818,804 0 0
GH RESEARCH PLC ORDINARY SHARES G3855L106   33,437,646 3,327,129 SH   SOLE   3,327,129 0 0
GUARDANT HEALTH INC COM 40131M109   14,846,291 500,887 SH   SOLE   500,887 0 0
ILLUMINA INC COM 452327109   25,825,800 188,125 SH   SOLE   188,125 0 0
IMMATICS N.V SHS N44445109   9,785,100 845,000 SH   SOLE   845,000 0 0
IMMUNIC INC COM 4525EP101   6,372,825 4,335,255 SH   SOLE   4,335,255 0 0
IMMUNOCORE HLDGS PLC ADS 45258D105   316,402,485 6,096,387 SH   SOLE   6,096,387 0 0
INSMED INC COM PAR $.01 457669307   47,093,977 1,865,108 SH   SOLE   1,865,108 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105   45,197,189 309,485 SH   SOLE   309,485 0 0
MASIMO CORP COM 574795100   131,650,906 1,501,493 SH   SOLE   1,501,493 0 0
MERUS N V COM N5749R100   47,083,695 1,996,764 SH   SOLE   1,996,764 0 0
MILESTONE PHARMACEUTICALS IN COM 59935V107   10,093,916 3,256,102 SH   SOLE   3,256,102 0 0
MINERALYS THERAPEUTICS INC COM 603170101   8,769,171 922,100 SH   SOLE   922,100 0 0
MIRATI THERAPEUTICS INC COM 60468T105   294,836,470 6,768,514 SH   SOLE   6,768,514 0 0
MIROMATRIX MED INC COM 60471P108   583,241 445,222 SH   SOLE   445,222 0 0
MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104   28,500,000 500,000 SH   SOLE   500,000 0 0
NATERA INC COM 632307104   117,341,398 2,651,783 SH   SOLE   2,651,783 0 0
OLINK HLDG AB SPONSORED ADS 680710100   2,413,867 163,652 SH   SOLE   163,652 0 0
ORCHESTRA BIOMED HLDGS INC COM 68572M106   49,011,981 5,620,640 SH   SOLE   5,620,640 0 0
OUTSET MED INC COM 690145107   8,798,199 808,658 SH   SOLE   808,658 0 0
PENUMBRA INC COM 70975L107   162,895,179 673,371 SH   SOLE   673,371 0 0
PMV PHARMACEUTICALS INC COM 69353Y103   14,587,320 2,375,785 SH   SOLE   2,375,785 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102   90,330,774 5,415,514 SH   SOLE   5,415,514 0 0
PTC THERAPEUTICS INC COM 69366J200   162,140,742 7,235,196 SH   SOLE   7,235,196 0 0
RAYZEBIO INC COM 75525N107   1,027,860 46,300 SH   SOLE   46,300 0 0
RELMADA THERAPEUTICS INC COM 75955J402   6,395,505 2,131,835 SH   SOLE   2,131,835 0 0
ROCKET PHARMACEUTICALS INC *W EXP 09/02/202 77313F114   59,500 350,000 SH   SOLE   350,000 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106   362,422,448 17,687,772 SH   SOLE   17,687,772 0 0
ROIVANT SCIENCES LTD SHS G76279101   18,135,735 1,552,717 SH   SOLE   1,552,717 0 0
SAGE THERAPEUTICS INC COM 78667J108   105,976,340 5,149,482 SH   SOLE   5,149,482 0 0
SAGIMET BIOSCIENCES INC COM SER A 786700104   3,522,438 400,277 SH   SOLE   400,277 0 0
SCPHARMACEUTICALS INC COM 810648105   23,480,642 3,297,843 SH   SOLE   3,297,843 0 0
SHOCKWAVE MED INC COM 82489T104   24,688,400 124,000 SH   SOLE   124,000 0 0
SIENTRA INC COM 82621J204   845,220 304,036 SH   SOLE   304,036 0 0
STOKE THERAPEUTICS INC COM 86150R107   17,298,799 4,390,558 SH   SOLE   4,390,558 0 0
STRYKER CORPORATION COM 863667101   7,651,560 28,000 SH   SOLE   28,000 0 0
TARSUS PHARMACEUTICALS INC COM 87650L103   51,190,057 2,880,701 SH   SOLE   2,880,701 0 0
TAYSHA GENE THERAPIES INC COM SHS 877619106   53,382,465 16,893,185 SH   SOLE   16,893,185 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102   146,958,361 290,334 SH   SOLE   290,334 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108   192,691,423 5,405,089 SH   SOLE   5,405,089 0 0
UROGEN PHARMA LTD COM M96088105   12,013,071 857,464 SH   SOLE   857,464 0 0
VERICEL CORP COM 92346J108   110,343,583 3,291,873 SH   SOLE   3,291,873 0 0
VIKING THERAPEUTICS INC COM 92686J106   2,871,558 259,400 SH   SOLE   259,400 0 0