0001493152-21-003922.txt : 20210216 0001493152-21-003922.hdr.sgml : 20210216 20210216144036 ACCESSION NUMBER: 0001493152-21-003922 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20201231 FILED AS OF DATE: 20210216 DATE AS OF CHANGE: 20210216 EFFECTIVENESS DATE: 20210216 FILER: COMPANY DATA: COMPANY CONFORMED NAME: RTW INVESTMENTS, LP CENTRAL INDEX KEY: 0001493215 IRS NUMBER: 000000000 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-16670 FILM NUMBER: 21636481 BUSINESS ADDRESS: STREET 1: 40 10TH AVENUE STREET 2: 7TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10014 BUSINESS PHONE: 646-597-6980 MAIL ADDRESS: STREET 1: 40 10TH AVENUE STREET 2: 7TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10014 FORMER COMPANY: FORMER CONFORMED NAME: RTW INVESTMENTS, LLC DATE OF NAME CHANGE: 20100602 13F-HR 1 primary_doc.xml 13F-HR LIVE false true false 0001493215 XXXXXXXX 12-31-2020 12-31-2020 false RTW INVESTMENTS, LP

40 10TH AVENUE 7TH FLOOR NEW YORK NY 10014

13F HOLDINGS REPORT 028-16670 N Roderick Wong 646-597-6980 /s/ Roderick Wong New York NY 02-16-2021 4 102 5960261 1 0001493219 028-16671 RTW MASTER FUND, LTD. 2 0001776733 028-19525 RTW Innovation Master Fund Ltd. 3 0001785169 028-19571 RTW Venture Fund Ltd 4 0001794051 028-19631 RTW Special Purpose Fund II, LLC INFORMATION TABLE 2 infotable.xml 10x Genomics Inc CL A COM 88025U109 93588 660933 SH SOLE 1,2,3 660933 0 0 5 01 Acquisition Corp COM CL A 33836P105 3987 392000 SH SOLE 1,2,3 392000 0 0 908 Devices Inc COM 65443P102 2278 40000 SH SOLE 1,2,3 40000 0 0 Acutus Med Inc COM 005111109 13017 451834 SH SOLE 1,2,3 451834 0 0 Adverum Biotechnologies Inc COM 00773U108 78345 7227364 SH SOLE 1,2,3 7227364 0 0 Agenus Inc COM NEW 00847G705 40910 12864677 SH SOLE 1,2,3 12864677 0 0 Alnylam Pharmaceuticals Inc COM 02043Q107 218563 1681645 SH SOLE 1,2,3 1681645 0 0 Aptevo Therapeutics Inc COM NEW 03835L207 10564 288236 SH SOLE 1,2,3 288236 0 0 Apyx Medical Corporation COM 03837C106 24417 3391279 SH SOLE 1,2,3 3391279 0 0 Arbutus Biopharma Corp COM 03879J100 21223 5978355 SH SOLE 1,2,3 5978355 0 0 argenx SE SPONSORED ADR 04016X101 9338 31752 SH SOLE 1,2 31752 0 0 Arvinas Inc COM 04335A105 152109 1790996 SH SOLE 1,2,3 1790996 0 0 Arya Sciences Acquisition Co COM CL A G3166W106 5425 500000 SH SOLE 1,2,3 500000 0 0 Athira Pharma Inc COM 04746L104 88899 2685779 SH SOLE 1,2,3 2685779 0 0 Avadel Pharmaceuticals plc SPONSORED ADR 05337M104 35989 5387513 SH SOLE 1,2,3 5387513 0 0 Avidity Biosciences Inc COM 05370A108 101952 3995000 SH SOLE 1,2,3 3995000 0 0 Axonics Modulation Technolog COM 05465P101 94042 1883864 SH SOLE 1,2,3 1883864 0 0 Axsome Therapeutics Inc COM 05464T104 136252 1672416 SH SOLE 1,2,3 1672416 0 0 Aziyo Biologics Inc COM CL A 05479K106 1704 125000 SH SOLE 1,2,3 125000 0 0 Bcls Acquisition Corp COM CL A G0904B105 6823 612500 SH SOLE 1,2,3 612500 0 0 BCTG Acquisition Corp COM 05492W103 6864 600000 SH SOLE 1,2,3 600000 0 0 Bellus Health Inc New COM NEW 07987C204 15778 5189862 SH SOLE 1,2,3 5189862 0 0 Berkeley Lts Inc COM 084310101 29034 324734 SH SOLE 1,2,3 324734 0 0 Bioatla Inc COM 09077B104 340 10000 SH SOLE 1,2,3 10000 0 0 Biodesix Inc COM 09075X108 2520 125000 SH SOLE 1,2,3 125000 0 0 BiomX Inc *W EXP 10/16/202 09090D111 480 600000 SH SOLE 1,2 600000 0 0 Biomx Inc COM 09090D103 3828 600000 SH SOLE 1,2 600000 0 0 Brainsway Ltd SPONSORED ADS 10501L106 8320 1103474 SH SOLE 1,2,3 1103474 0 0 Burning Rock Biotech Ltd SPONSORED ADS 12233L107 693 30000 SH SOLE 1,2,3 30000 0 0 C4 Therapeutics Inc COM STK 12529R107 68679 2149228 SH SOLE 1,2,3 2149228 0 0 Castle Biosciences Inc COM 14843C105 53653 799009 SH SOLE 1,2,3 799009 0 0 Celldex Therapeutics Inc New COM NEW 15117B202 59968 3422855 SH SOLE 1,2,3 3422855 0 0 Cerevel Therapeutics Hldng I COM 15678U128 8290 500000 SH SOLE 1,2,3 500000 0 0 Cerevel Therapeutics Hldng I *W EXP 06/09/202 15678U102 942 166666 SH SOLE 1,2,3 166666 0 0 Cerner Corp COM 156782104 133548 1701680 SH SOLE 1,2,3 1701680 0 0 Chardan Healthcr Acqstn 2 Co UNIT 99/99/9999 15957T206 3707 350000 SH SOLE 1,2,3 350000 0 0 Clearside Biomedical Inc COM 185063104 10845 3958130 SH SOLE 1,2,3 3958130 0 0 Curis Inc COM NEW 231269200 30527 3727360 SH SOLE 1,2,3 3727360 0 0 Cytokinetics Inc COM NEW 23282W605 41311 2000000 SH SOLE 1,2,3 2000000 0 0 Cytomx Therapeutics Inc COM 23284F105 10004 1527352 SH SOLE 1,2,3 1527352 0 0 DermTech Inc COM 24984K105 93661 2887215 SH SOLE 1,2,3 2887215 0 0 Dicerna Pharmaceuticals Inc COM 253031108 159802 7253857 SH SOLE 1,2,3 7253857 0 0 Establishment Labs Hldgs Inc COM G31249108 87292 2319138 SH SOLE 1,2,3 2319138 0 0 Exagen Inc COM 30068X103 16502 1250131 SH SOLE 1,2,3 1250131 0 0 Five Prime Therapeutics Inc COM 33830X104 42794 2515788 SH SOLE 1,2,3 2515788 0 0 Frequency Therapeutics Inc COM 35803L108 86792 2461486 SH SOLE 1,2,3 2461486 0 0 Fulcrum Therapeutics Inc COM 359616109 24256 2071409 SH SOLE 1,2,3 2071409 0 0 GenMark Diagnostics Inc COM 372309104 11140 762994 SH SOLE 1,2,3 762994 0 0 Globus Med Inc CL A 379577208 107017 1640859 SH SOLE 1,2,3 1640859 0 0 Guardant Health Inc COM 40131M109 75004 581970 SH SOLE 1,2,3 581970 0 0 Helix Acquisition Corp COM CL A G4444C102 8528 750000 SH SOLE 1,2,3 750000 0 0 Ideaya Biosciences Inc COM 45166A102 25856 1846843 SH SOLE 1,2,3 1846843 0 0 Illumina Inc COM 452327109 133858 361778 SH SOLE 1,2,3 361778 0 0 Immatics N.V SHS N44445109 3777 350000 SH SOLE 1,2,3 350000 0 0 Immunic Inc COM 4525EP101 14079 920814 SH SOLE 1,2,3 920814 0 0 Immunovant Inc COM 45258J102 350686 7592253 SH SOLE 1,2,3 7592253 0 0 Inmode Ltd SHS M5425M103 5935 124999 SH SOLE 1,2 124999 0 0 Itamar Med Ltd SPONSORED ADS 465437101 4540 228609 SH SOLE 1,2,3 228609 0 0 Iteos Therapeutics Inc COM 46565G104 35975 1074166 SH SOLE 1,2,3 1074166 0 0 IVERIC bio Inc COM 46583P102 46453 6722624 SH SOLE 1,2,3 6722624 0 0 Johnson & Johnson COM 478160104 23569 149761 SH SOLE 1,2,3 149761 0 0 Kura Oncology Inc COM 50127T109 55580 1701781 SH SOLE 1,2,3 1701781 0 0 La Jolla Pharmaceutical Co COM PAR $.0001 2 503459604 9302 2397378 SH SOLE 1,2,3 2397378 0 0 Lifesci Acquisition Ii Corp COM 53229E103 6936 650000 SH SOLE 1,2,3 650000 0 0 MacroGenics Inc COM 556099109 28722 1256409 SH SOLE 1,2,3 1256409 0 0 Maravai Lifesciences Hldgs I COM CL A 56600D107 1964 70000 SH SOLE 1,2,3 70000 0 0 Masimo Corp COM 574795100 125982 469416 SH SOLE 1,2,3 469416 0 0 Milestone Pharmaceuticals In COM 59935V107 28911 4315102 SH SOLE 1,2,3 4315102 0 0 MiMedx Group Inc COM 602496101 24519 2700320 SH SOLE 1,2,3 2700320 0 0 Mirati Therapeutics Inc COM 60468T105 231581 1054364 SH SOLE 1,2,3 1054364 0 0 NanoString Technologies Inc COM 63009R109 53773 804029 SH SOLE 1,2,3 804029 0 0 Natera Inc COM 632307104 170402 1712234 SH SOLE 1,2,3 1712234 0 0 Odonate Therapeutics Inc COM 676079106 19203 1000139 SH SOLE 1,2,3 1000139 0 0 OraSure Technologies Inc COM 68554V108 1948 184000 SH SOLE 1,2,3 184000 0 0 Outset Med Inc COM 690145107 33256 585074 SH SOLE 1,2,3 585074 0 0 Oyster Pt Pharma Inc COM 69242L106 36240 1925594 SH SOLE 1,2,3 1925594 0 0 Panacea Acquisition Corp UNIT 99/99/9999 698102209 3828 300000 SH SOLE 1,2,3 300000 0 0 Penumbra Inc COM 70975L107 20698 118273 SH SOLE 1,2,3 118273 0 0 Personalis Inc COM 71535D106 4668 127501 SH SOLE 1,2 127501 0 0 Pmv Pharmaceuticals Inc COM 69353Y103 30809 500882 SH SOLE 1,2,3 500882 0 0 Profound Med Corp COM NEW 74319B502 2510 122098 SH SOLE 1,2,3 122098 0 0 Progenity Inc COM 74319F107 531 100000 SH SOLE 1,2,3 100000 0 0 ProQR Thrapeutics N V SHS EURO N71542109 21041 5009768 SH SOLE 1,2,3 5009768 0 0 Protagonist Therapeutics Inc COM 74366E102 73585 3650069 SH SOLE 1,2,3 3650069 0 0 PTC Therapeutics Inc COM 69366J200 257659 4221836 SH SOLE 1,2,3 4221836 0 0 Pulmonx Corp COM 745848101 74839 1129600 SH SOLE 1,2,3 1129600 0 0 Regenxbio Inc COM 75901B107 12803 282260 SH SOLE 1,2,3 282260 0 0 Relmada Therapeutics Inc COM 75955J402 48511 1512673 SH SOLE 1,2,3 1512673 0 0 Rocket Pharmaceuticals Inc COM 77313F106 935582 17060211 SH SOLE 1,2,3,4 17060211 0 0 Scholar Rock Hldg Corp COM 80706P103 8065 166183 SH SOLE 1,2,3 166183 0 0 Seer Inc COM CL A 81578P106 225 4000 SH SOLE 1,2,3 4000 0 0 Stoke Therapeutics Inc COM 86150R107 219495 3544248 SH SOLE 1,2,3 3544248 0 0 Tandem Diabetes Care Inc COM NEW 875372203 63243 660982 SH SOLE 1,2,3 660982 0 0 Tarsus Pharmaceuticals Inc. COM 87650L103 98987 2463601 SH SOLE 1,2,3 2463601 0 0 Tela Bio Inc COM 872381108 20813 1383816 SH SOLE 1,2,3 1383816 0 0 Therapeutics Acquisition Cor COM CL A 88339T103 6821 490000 SH SOLE 1,2,3 490000 0 0 Translate Bio Inc COM 89374L104 54892 2978427 SH SOLE 1,2,3 2978427 0 0 Trillium Therapeutics Inc COM NEW 89620X506 31850 2165197 SH SOLE 1,2,3 2165197 0 0 Twist Bioscience Corp COM 90184D100 2610 18473 SH SOLE 1,2,3 18473 0 0 Vericel Corp COM 92346J108 139503 4517570 SH SOLE 1,2,3 4517570 0 0 Vincera Pharma Inc *W EXP 12/24/202 92731L114 1650 500000 SH SOLE 1,2,3 500000 0 0 Vincera Pharma Inc COM 92731L106 10455 500000 SH SOLE 1,2,3 500000 0 0