Leases - Additional Information (Detail) - USD ($)		1 Months Ended							9 Months Ended
	Nov. 30, 2014	Sep. 30, 2022	Sep. 30, 2021	Oct. 31, 2020	Aug. 31, 2018	Sep. 30, 2017	Apr. 30, 2015	Nov. 30, 2014	Sep. 30, 2022	Dec. 31, 2021	Dec. 31, 2019
Leases [Line Items]
Operating lease right-of-use assets		$ 9,058,000							$ 9,058,000	$ 9,766,000
License Agreement [Member] | Operating Lease Entered into November 2014 [Member] | Office Space [Member]
Leases [Line Items]
Lease expiration date						Dec. 31, 2021	Dec. 31, 2017
Security deposit	$ 50,000							$ 50,000
Lease termination date	Dec. 31, 2021
Office Space, Laboratory Space, and Equipment [Member]
Leases [Line Items]
Operating lease right-of-use assets		0							0
Lease liabilities		0							$ 0
Maximum lease period to not recognize right of use assets or lease liabilities									12 months
Office Laboratory And Manufacturing Space | Operating Leases Entered Into May2013
Leases [Line Items]
Operating lease right-of-use assets		200,000							$ 200,000
Lease liabilities		$ 200,000							200,000
Lease expiration date		Dec. 31, 2024		Dec. 31, 2022	Dec. 31, 2020
Laboratory Space [Member] | Operating Lease Entered into November 2014 [Member]
Leases [Line Items]
Lease expiration date				Oct. 31, 2025
Security deposit		$ 130,977							130,977		$ 281,000
Term of lease	6 years							6 years
Space build-out costs paid	$ 1,400,000							$ 1,400,000
Space build-out costs								$ 2,200,000
Security deposit received from landlord										$ 281,000
Office, Research, Laboratory and Manufacturing Space [Member] | Operating Leases Entered Into September 2021 [Member]
Leases [Line Items]
Operating lease right-of-use assets		0							0
Lease liabilities		0							0
Security deposit		$ 1,000,000.0							$ 1,000,000.0
Term of lease			126 months