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Nature of Business (Details) - USD ($)
$ in Thousands
Aug. 12, 2014
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Cash and cash equivalents   $ 73,662 $ 73,849 $ 30,198 $ 9,709
Accumulated deficit   (148,885) $ (103,595)    
Period over which cash resources will be sufficient to allow Company to fund current operating plan 12 months        
Note Agreement 1          
Remaining borrowing capacity   $ 10,000