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Stockholders' Equity (Details 2) (USD $)
 3 Months Ended
Mar. 31, 2015
Mar. 31, 2014
Stock-based compensation expense    
Stock-based compensation expense $ 722,000us-gaap_AllocatedShareBasedCompensationExpense $ 239,000us-gaap_AllocatedShareBasedCompensationExpense
Total unrecognized compensation costs related to non-vested stock options 11,480,000us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions  
Remaining weighted-average period that unrecognized compensation costs are expected to be recognized 3 years 4 months 24 days  
Research and development    
Stock-based compensation expense    
Stock-based compensation expense 280,000us-gaap_AllocatedShareBasedCompensationExpense
/ us-gaap_IncomeStatementLocationAxis
= us-gaap_ResearchAndDevelopmentExpenseMember		 56,000us-gaap_AllocatedShareBasedCompensationExpense
/ us-gaap_IncomeStatementLocationAxis
= us-gaap_ResearchAndDevelopmentExpenseMember
Selling, general and administrative    
Stock-based compensation expense    
Stock-based compensation expense $ 442,000us-gaap_AllocatedShareBasedCompensationExpense
/ us-gaap_IncomeStatementLocationAxis
= us-gaap_SellingGeneralAndAdministrativeExpensesMember		 $ 183,000us-gaap_AllocatedShareBasedCompensationExpense
/ us-gaap_IncomeStatementLocationAxis
= us-gaap_SellingGeneralAndAdministrativeExpensesMember