X0306 4 2020-01-01 0 0001492674 T2 Biosystems, Inc. TTOO 0001292650 Elsbree David B 101 HARTWELL AVENUE LEXINGTON MA 02421 1 0 0 0 Common Stock 2020-01-01 4 M 0 13289 A 96397 D Common Stock 10000 I By spouse Restricted Stock Units 2020-01-01 4 A 0 34188 0.00 A Common Stock 34188 34188 D Restricted Stock Units 2020-01-01 4 M 0 13289 0.00 A Common Stock 13289 13289 D Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock. The reporting person disclaims ownership of these securities and this report shall not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 or for any other purpose. The restricted stock units were granted in accordance with the Issuer's Non-Employee Director Compensation Plan and vest on January 1, 2021. On January 1, 2019 the reporting person was granted 13,289 restricted stock units that vested on January 1, 2020. /s/ John Sprague, Attorney-in-Fact 2020-01-03