X0306 4 2017-11-30 0 0001492674 T2 Biosystems, Inc. TTOO 0001665000 Gibbs Michael Terrence 101 HARTWELL AVENUE LEXINGTON MA 02421 0 1 0 0 General Counsel Common Stock 2017-11-30 4 M 0 6500 A 50687 D Common Stock 2018-11-30 4 M 0 6500 A 57187 D Common Stock 2019-01-31 4 S 0 939 3.35 D 56248 D Common Stock 2019-02-01 4 S 0 1820 3.47 D 54428 D Restricted Stock Units 2017-11-30 4 M 0 6500 0.00 D Common Stock 6500 0 D Restricted Stock Units 2018-11-30 4 M 0 6500 0.00 D Common Stock 6500 0 D Each restricted stock units ("RSU's") represents a contingent right to receive one share of the Issuer's common stock. Includes 1,220 shares acquired under the Issuer's employee stock purchase plan on November 15, 2018. The price reported is a weighted average price. These shares were sold in multiple transactions at per share prices ranging from $3.32 to $3.39. The reporting person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. The price reported is a weighted average price. These shares were sold in multiple transactions at per share prices ranging from $3.34 to $3.55. The reporting person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. On November 30, 2016 the reporting person was granted 13,000 RSU's that vested in two equal annual installments beginning on November 30, 2017. /s/ John Sprague, Attorney-in-fact 2019-02-05