Accrued Trade Discounts and Rebates (Tables)

3 Months Ended

Mar. 31, 2022

Valuation And Qualifying Accounts Disclosure [Line Items]

Schedule of Accrued Expenses and Other Current Liabilities

Accrued expenses and other current liabilities as of March 31, 2022 and December 31, 2021 consisted of the following (in thousands):

	March 31, 2022		December 31, 2021
Accrued royalties	$	86,519	$	108,215
Payroll-related expenses		83,789		147,439
R&D and manufacturing programs		51,711		54,076
Allowances for returns		28,971		33,881
Advertising and marketing		22,995		16,930
Pricing review liability		22,838		21,075
Consulting and professional services		19,757		33,334
Refund liability ⁽¹⁾		15,155		16,711
Accrued interest		6,524		14,989
Accrued upfront and milestone payments		—		35,100
Accrued other		39,174		41,265
Accrued expenses and other current liabilities	$	377,433	$	523,015

(1)

The refund liability represents the amount of consideration that the Company may need to refund to MTPC if they don’t sell the product that was shipped to them. The refund liability is remeasured at each reporting date to reflect changes in the estimate of variable consideration, with a corresponding adjustment to revenue. Amounts expected to be settled within the 12 months following the balance sheet date are classified as current liabilities in the accompanying balance sheets. Amounts not expected to be settled within the 12 months following the condensed consolidated balance sheet date are classified as long-term liabilities. The following represents the changes to the refund liability for the three months ended March 31, 2022 (in thousands):


Refund liability at December 31, 2021	$	16,711
Shipments during the quarter		14,892
Remeasurement of refund liability recognized as revenue		(1,556	)
Refund liability at March 31, 2022	$	30,047
Less: current portion		15,155
Refund liability, net of current portion	$	14,892

Accrued Trade Discounts and Rebates [Member]

Valuation And Qualifying Accounts Disclosure [Line Items]

Schedule of Accrued Expenses and Other Current Liabilities

Accrued trade discounts and rebates as of March 31, 2022 and December 31, 2021 consisted of the following (in thousands):

	March 31, 2022		December 31, 2021
Accrued government rebates and chargebacks	$	278,537	$	222,632
Accrued commercial rebates and wholesaler fees		43,154		48,761
Accrued co-pay and other patient assistance		43,041		46,038
Accrued trade discounts and rebates	$	364,732	$	317,431
Invoiced commercial rebates and wholesaler fees, co-pay and other patient assistance, and government rebates and chargebacks in accounts payable		3,027		—
Total customer-related accruals and allowances	$	367,759	$	317,431

Valuation And Qualifying Accounts Disclosure [Line Items]

Schedule of Customer-Related Accruals and Allowances

The following table summarizes changes in the Company’s customer-related accruals and allowances from December 31, 2021 to March 31, 2022 (in thousands):

	Government Rebates and Chargebacks			Commercial Rebates and Wholesaler Fees			Co-Pay and Other Patient Assistance			Total
Balance at December 31, 2021	$	222,632		$	48,761		$	46,038		$	317,431
Current provisions relating to sales during the three months ended March 31, 2022		205,692			49,874			88,209			343,775
Adjustments relating to prior-year sales		(10,194	)		1,449			(3,395	)		(12,140	)
Payments relating to sales during the three months ended March 31, 2022		(58,781	)		(10,972	)		(49,514	)		(119,267	)
Payments relating to prior-year sales		(80,812	)		(42,931	)		(38,297	)		(162,040	)
Balance at March 31, 2022	$	278,537		$	46,181		$	43,041		$	367,759