Condensed Consolidated Balance Sheets (Unaudited) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
CURRENT ASSETS:
Cash and cash equivalents	$ 1,643,129	$ 1,580,317
Restricted cash	4,136	3,839
Accounts receivable, net	684,507	632,775
Inventories, net	226,524	225,730
Prepaid expenses and other current assets	389,435	357,106
Total current assets	2,947,731	2,799,767
Property, plant and equipment, net	295,147	292,298
Developed technology and other intangible assets, net	2,871,979	2,960,118
In-process research and development	880,000	880,000
Goodwill	1,066,709	1,066,709
Deferred tax assets, net	516,317	538,098
Other assets	162,455	140,738
Total assets	8,740,338	8,677,728
CURRENT LIABILITIES:
Accounts payable	67,014	30,125
Accrued expenses and other current liabilities	377,433	523,015
Accrued trade discounts and rebates	364,732	317,431
Long-term debt—current portion	16,000	16,000
Total current liabilities	825,179	886,571
LONG-TERM LIABILITIES:
Long-term debt, net	2,552,741	2,555,233
Deferred tax liabilities, net	334,778	390,455
Other long-term liabilities	209,811	173,076
Total long-term liabilities	3,097,330	3,118,764
COMMITMENTS AND CONTINGENCIES
SHAREHOLDERS’ EQUITY:
Ordinary shares, $0.0001 nominal value; 600,000,000 shares authorized at March 31, 2022 and December 31, 2021; 229,873,900 and 227,760,936 shares issued at March 31, 2022 and December 31, 2021, respectively; and 229,489,534 and 227,376,570 shares outstanding at March 31, 2022 and December 31, 2021, respectively	23	23
Treasury stock, 384,366 ordinary shares at March 31, 2022 and December 31, 2021	(4,585)	(4,585)
Additional paid-in capital	4,314,647	4,373,337
Accumulated other comprehensive loss	(15,122)	(14,987)
Retained earnings	522,866	318,605
Total shareholders’ equity	4,817,829	4,672,393
Total liabilities and shareholders' equity	$ 8,740,338	$ 8,677,728