Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands	3 Months Ended	6 Months Ended		12 Months Ended
	Jun. 30, 2019	Jun. 30, 2020	Jun. 30, 2019	Dec. 31, 2019
CASH FLOWS FROM OPERATING ACTIVITIES:
Net loss		$ (93,601)	$ (37,983)
Adjustments to reconcile net loss to net cash provided by operating activities:
Depreciation and amortization expense		139,396	118,017
Equity-settled share-based compensation		83,478	48,915
Acquired in-process research and development expense		47,517
Loss on debt extinguishment		17,254	17,464
Amortization of debt discount and deferred financing costs		10,817	11,622
Loss on sale of assets	$ 10,963		10,963
Deferred income taxes		(4,561)	(1,257)
Foreign exchange and other adjustments		661	493
Changes in operating assets and liabilities:
Accounts receivable		(135,125)	69,787
Inventories		(12,343)	(504)
Prepaid expenses and other current assets		(20,410)	(17,696)
Accounts payable		83,555	11,554
Accrued trade discounts and rebates		(177,721)	(59,151)
Accrued expenses		81,505	(28,071)
Deferred revenues			2,410
Other non-current assets and liabilities		16,586	873
Net cash provided by operating activities		37,008	147,436
CASH FLOWS FROM INVESTING ACTIVITIES:
Payments for acquisitions		(262,305)
Purchases of property and equipment		(119,970)	(6,858)
Change in escrow deposit for property purchase		6,000
Proceeds from sale of assets			6,000
Net cash used in investing activities		(376,275)	(858)
CASH FLOWS FROM FINANCING ACTIVITIES:
Net proceeds from the issuance of ordinary shares			326,793
Repayment of term loans			(818,026)
Repayment of senior notes			(258,282)
Net proceeds from term loans			517,378
Proceeds from the issuance of ordinary shares in conjunction with ESPP program		7,979	5,465
Proceeds from the issuance of ordinary shares in connection with stock option exercises		25,887	12,029
Payment of employee withholding taxes relating to share-based awards		(53,009)	(24,374)
Net cash used in financing activities		(19,143)	(239,017)
Effect of foreign exchange rate changes on cash, cash equivalents and restricted cash		58	58
Net decrease in cash, cash equivalents and restricted cash		(358,352)	(92,381)
Cash, cash equivalents and restricted cash, beginning of the period		1,080,039	962,117	$ 962,117
Cash, cash equivalents and restricted cash, end of the period	$ 869,736	721,687	869,736	$ 1,080,039
SUPPLEMENTAL CASH FLOW INFORMATION:
Cash paid for interest		30,068	49,516
Cash paid for amounts included in the measurement of lease liabilities		3,797	2,906
Cash paid for income taxes, net of refunds received		597	7,644
SUPPLEMENTAL NON-CASH FLOW INFORMATION:
Principal amount of Exchangeable Senior Notes exchanged for ordinary shares		207,044
Purchases of property and equipment included in accounts payable and accrued expenses		2,912	$ 1,941
TEPEZA [Member]
SUPPLEMENTAL NON-CASH FLOW INFORMATION:
Milestone payments for TEPEZZA intangible asset included in accrued expenses		$ 98,606