Accrued Trade Discounts and Rebates - Schedule of Customer-Related Accruals and Allowances (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Government Rebates and Chargebacks [Member]
Valuation And Qualifying Accounts Disclosure [Line Items]
Beginning Balance	$ 222,632	$ 172,893
Current provisions relating to sales	823,299	756,222
Adjustments relating to prior-year sales	(30,405)	(21,077)
Payments relating to sales	(529,311)	(538,086)
Payments relating to prior-year sales	(190,657)	(148,731)
Ending Balance	295,558	222,632
Government Rebates and Chargebacks [Member] | Viela [Member]
Valuation And Qualifying Accounts Disclosure [Line Items]
Viela acquisition		1,411
Commercial Rebates and Wholesaler Fees [Member]
Valuation And Qualifying Accounts Disclosure [Line Items]
Beginning Balance	48,761	84,098
Current provisions relating to sales	195,937	282,005
Adjustments relating to prior-year sales	2,118	(2,921)
Payments relating to sales	(153,462)	(233,314)
Payments relating to prior-year sales	(47,195)	(81,177)
Ending Balance	46,159	48,761
Commercial Rebates and Wholesaler Fees [Member] | Viela [Member]
Valuation And Qualifying Accounts Disclosure [Line Items]
Viela acquisition		70
Co-Pay and Other Patient Assistance [Member]
Valuation And Qualifying Accounts Disclosure [Line Items]
Beginning Balance	46,038	96,924
Current provisions relating to sales	345,430	604,209
Adjustments relating to prior-year sales	(3,497)	(4,516)
Payments relating to sales	(290,028)	(558,182)
Payments relating to prior-year sales	(42,530)	(92,408)
Ending Balance	55,413	46,038
Co-Pay and Other Patient Assistance [Member] | Viela [Member]
Valuation And Qualifying Accounts Disclosure [Line Items]
Viela acquisition		11
Customer-related Accruals and Allowances [Member]
Valuation And Qualifying Accounts Disclosure [Line Items]
Beginning Balance	317,431	353,915
Current provisions relating to sales	1,364,666	1,642,436
Adjustments relating to prior-year sales	(31,784)	(28,514)
Payments relating to sales	(972,801)	(1,329,582)
Payments relating to prior-year sales	(280,382)	(322,316)
Ending Balance	$ 397,130	317,431
Customer-related Accruals and Allowances [Member] | Viela [Member]
Valuation And Qualifying Accounts Disclosure [Line Items]
Viela acquisition		$ 1,492