Goodwill and Intangible Assets - Additional Information (Detail) - USD ($) $ in Thousands		1 Months Ended		12 Months Ended
	Mar. 15, 2021	Jun. 30, 2022	Jul. 31, 2021	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Finite-Lived Intangible Assets [Line Items]
Goodwill				$ 1,010,538	$ 1,066,709
Impairment of goodwill				56,171
Amortization expense of developed technology				366,500	$ 336,300	$ 255,100
UPLIZNA [Member] | Developed Technology [Member]
Finite-Lived Intangible Assets [Line Items]
Capitalized payments of intangible assets	$ 1,460,000
EirGen Pharma Limited [Member]
Finite-Lived Intangible Assets [Line Items]
Capitalized payments of intangible assets			$ 21,800
Finite-lived intangible assets, remaining amortization period			16 years
Viela Acquisition [Member]
Finite-Lived Intangible Assets [Line Items]
Capitalized payments of intangible assets				$ 810,000
Inflammation Reporting Unit
Finite-Lived Intangible Assets [Line Items]
Impairment of goodwill		$ 56,200