Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2025	Jun. 30, 2024	Jun. 30, 2025	Jun. 30, 2024
Revenue:
Revenue	$ 178,494	$ 199,685	$ 345,291	$ 372,009
Operating expenses:
Cost of sales	13,626	23,100	47,986	43,309
Research and development	67,015	77,947	153,435	162,647
Selling, general and administrative	131,139	128,081	260,484	257,587
Total operating expenses:	211,780	229,128	461,905	463,543
Net operating loss	(33,286)	(29,443)	(116,614)	(91,534)
Loss on extinguishment of development liability		(1,949)		(1,949)
Interest income	2,607	3,184	5,265	6,488
Interest expense	(11,152)	(9,359)	(22,201)	(16,326)
Other income/(expense), net	146	24	(19)	(475)
Net loss before taxes	(41,685)	(37,543)	(133,569)	(103,796)
Income tax expense	466	114	807	284
Net loss	(42,151)	(37,657)	(134,376)	(104,080)
Other comprehensive gain:
Foreign currency translation	485	163	739	180
Total other comprehensive income	485	163	739	180
Comprehensive loss, net of tax	$ (41,666)	$ (37,494)	$ (133,637)	$ (103,900)
Net loss per common share, basic	$ (0.33)	$ (0.3)	$ (1.07)	$ (0.84)
Net loss per common share, diluted	$ (0.33)	$ (0.3)	$ (1.07)	$ (0.84)
Weighted-average number of common shares used in net loss per common share, basic	126,024	123,904	125,740	123,430
Weighted-average number of common shares used in net loss per common share, diluted	126,024	123,904	125,740	123,430
Product revenue, net [Member]
Revenue:
Revenue	$ 171,387	$ 179,136	$ 321,287	$ 342,211
Licensing and other revenue [Member]
Revenue:
Revenue	$ 7,107	$ 20,549	$ 24,004	$ 29,798