Development Liability and Development Derivative Liability - Additional Information (Detail) $ in Thousands			1 Months Ended			3 Months Ended			6 Months Ended
	Jan. 29, 2020 USD ($)	Feb. 28, 2019 USD ($) Installment	May 31, 2022 USD ($)	Jan. 31, 2022 USD ($)	Jun. 30, 2021 USD ($)	Jun. 30, 2022 USD ($)	Jun. 30, 2021 USD ($)	Mar. 31, 2021 USD ($)	Jun. 30, 2022 USD ($)	Jun. 30, 2021 USD ($)	Jun. 07, 2019 USD ($)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Interest expense						$ 8,448	$ 3,767		$ 16,986	$ 7,941
Loss from remeasurement of development derivative liability							$ 21,180	$ 17,084		$ 38,264
Level 3 [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Implied cost of borrowing discount rates										11.15%
SFJ Agreement [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Proceeds from SFJ agreement	$ 140,000	$ 60,000
Additional funding amount upon achievement of development milestones		$ 60,000
Number of milestone payments | Installment		3
Increase in additional funding for development costs											$ 20,000
Payment made under agreement				$ 5,000	$ 4,000
First annual payment under agreement			$ 11,500
Interest expense						$ 6,600			$ 13,300
SFJ Agreement [Member] | Level 3 [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Implied cost of borrowing discount rates										8.00%
SFJ Agreement [Member] | Regulatory Approval Granted US Food and Drug Administration [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Obligated to pay initial payment		$ 4,000
Aggregate amount of additional annual payments		$ 226,000
Number of additional annual payments | Installment		6
SFJ Agreement [Member] | Regulatory Approval Granted by EMA [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Obligated to pay initial payment		$ 5,000
Aggregate amount of additional annual payments		$ 225,000
Number of additional annual payments | Installment		6