Prepaid Assets and Accrued Expenses - Schedule of Accrued Expenses (Detail) - USD ($) $ in Thousands	Jun. 30, 2022	Dec. 31, 2021
Prepaid Assets And Accrued Expenses [Abstract]
Accrued research and development	$ 39,006	$ 35,217
Accrued cost of research collaboration		25,000
Accrued license fee		5,000
Accrued royalties	1,042
Accrued payroll liabilities	22,182	25,212
Other	27,189	12,810
Total	$ 89,419	$ 103,239