Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Jun. 30, 2022	Dec. 31, 2021	Jun. 30, 2021
Current assets:
Cash and cash equivalents	$ 604,489	$ 640,192	$ 270,764
Marketable securities	248,307	60,358
Accounts receivable	7,518	10,103
Inventory	48,451	16,286
Prepaid assets	21,478	24,868
Restricted cash	1,266	1,563
Other current assets	28,460	70,677
Total current assets	959,969	824,047
Non-current assets:
Right-of-use assets	20,755	19,901
Property and equipment, net	5,892	6,177
Other assets	15,882	31,640
Total assets	1,002,498	881,765
Current liabilities:
Accounts payable	16,220	16,909
Accrued expenses	89,419	103,239
Current portion of development liability	15,842	7,584
Current portion of right-of-use liabilities	5,312	4,115
Total current liabilities	126,793	131,847
Long-term liabilities:
Long-term development liability	333,729	345,151
Convertible senior notes	189,313	189,024
Right-of-use liabilities	16,676	17,081
Other liabilities	1,569
Total liabilities	668,080	683,103
Commitments and contingencies (Note 14)
Stockholders' equity:
Preferred stock, $0.0001 par value; 10,000 shares authorized, and zero shares issued and outstanding at June 30, 2022 and December 31, 2021	0	0
Common stock, $0.0001 par value; 200,000 shares authorized at June 30, 2022 and December 31, 2021; 106,841 shares issued and outstanding at June 30, 2022, and 97,524 shares issued and outstanding at December 31, 2021	11	10
Additional paid-in capital	2,289,201	1,857,430
Accumulated other comprehensive loss	(3,194)	(2,090)
Accumulated deficit	(1,951,600)	(1,656,688)
Total stockholders' equity	334,418	198,662	$ (141,493)
Total liabilities and stockholders' equity	$ 1,002,498	$ 881,765