X0306 4 2023-01-01 0 0001492422 Apellis Pharmaceuticals, Inc. APLS 0001727550 FONTEYNE PAUL R. C/O APELLIS PHARMACEUTICALS, INC. 100 FIFTH AVENUE WALTHAM MA 02451 1 0 0 0 Common Stock 2023-01-01 4 A 0 3867 0.00 A 13097 D Stock Option (Right to Buy) 51.71 2023-01-01 4 A 0 7441 0.00 A 2030-12-31 Common Stock 7441 7441 D This restricted stock unit was granted on January 1, 2023. The restricted stock unit will fully vest on the first anniversary of the date of grant, subject to his continued service as a director, or upon later termination of his service as a director at his election. This option was granted on January 1, 2023. The option vests quarterly on the last day of each quarter from the date of grant, subject to his continued service as a director and expires seven years after the date of grant. /s/ David Watson, attorney-in-fact for Paul Fonteyne 2023-01-04