X0206 3 2020-09-25 0 0001492422 Apellis Pharmaceuticals, Inc. APLS 0001827326 Eisele Jeffrey C/O APELLIS PHARMACEUTICALS, INC. 100 FIFTH AVENUE, 3RD FLOOR WALTHAM MA 02451 0 1 0 0 See Remarks Stock Option (Right to Buy) 30.45 2030-08-31 Common Stock 125000 D This stock option was granted on September 1, 2020 and will vest as to 25% of the shares underlying the options on the first anniversary of the grant, with the remaining 75% of the shares underlying the options vesting in equal monthly installments thereafter through the fourth anniversary of the grant date, subject to continued service. Executive Vice President, Program Team Lead Exhibit 24 - Power of Attorney /s/ David Watson, Attorney-in-fact for Jeffrey Eisele 2020-10-06