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Intangible Assets (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2018
Mar. 31, 2018
Mar. 31, 2017
Dec. 31, 2017
Intangible Assets        
Acquired and in-licensed rights $ 64,665 $ 64,665   $ 64,665
Less: accumulated amortization (9,718) (9,718)   (8,281)
Total intangible asset, net 54,947 54,947   $ 56,384
Amortization expense 1,400   $ 500  
Estimated future amortization expense        
2018 4,500 4,500    
2019 6,000 6,000    
2020 6,000 6,000    
2021 6,000 6,000    
2022 6,000 6,000    
Thereafter $ 26,500 $ 26,500    
Use Rights [Member] | Minimum        
Intangible Assets        
Estimated useful life   8 years    
Use Rights [Member] | Maximum        
Intangible Assets        
Estimated useful life   15 years