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Net Loss per Share (Details) - shares
shares in Thousands
3 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Net Loss per Share    
Amounts excluded from the calculation of diluted net loss per share due to their anti-dilutive effect 12,645 7,625
Outstanding stock awards and Employee Stock Purchase Plan    
Net Loss per Share    
Amounts excluded from the calculation of diluted net loss per share due to their anti-dilutive effect 7,366 7,068
Unvested restricted stock units    
Net Loss per Share    
Amounts excluded from the calculation of diluted net loss per share due to their anti-dilutive effect 1,093 537
Shares issuable upon conversion of Convertible Notes    
Net Loss per Share    
Amounts excluded from the calculation of diluted net loss per share due to their anti-dilutive effect 4,186 20