SCHEDULE 13G 0001491072 XXXXXXXX LIVE Common Stock, $0.00001 par value 03/31/2025 0001347858 22nd Century Group, Inc. 90137F301 8560 MAIN STREET, SUITE 4 WILLIAMSVILLE NY 14221 Rule 13d-1(b) Anson Funds Management LP TX 0 176094 0 176094 176094 N 7.4 IA PN Anson Management GP LLC TX 0 176094 0 176094 176094 N 7.4 HC OO Tony Moore X1 0 176094 0 176094 176094 N 7.4 HC IN Anson Advisors Inc. Z4 0 176094 0 176094 176094 N 7.4 FI CO Amin Nathoo Z4 0 176094 0 176094 176094 N 7.4 HC IN Moez Kassam Z4 0 176094 0 176094 176094 N 7.4 HC IN 22nd Century Group, Inc. 8560 MAIN STREET, SUITE 4, WILLIAMSVILLE, NY, 14221 Anson Funds Management LP, Anson Management GP LLC, Mr. Tony Moore, Anson Advisors Inc., Mr. Amin Nathoo and Mr. Moez Kassam For Anson Funds Management LP, Anson Management GP LLC and Mr. Moore: 16000 Dallas Parkway, Suite 800 Dallas, Texas 75248 For Anson Advisors Inc., Mr. Nathoo and Mr. Kassam: 181 Bay Street, Suite 4200 Toronto, ON M5J 2T3 Anson Funds Management LP is a limited partnership organized under the laws of the State of Texas. Anson Management GP LLC is a limited liability company organized under the laws of the State of Texas. Mr. Moore is a United States citizen. Anson Advisors Inc. is a corporation organized under the laws of Ontario, Canada. Mr. Nathoo and Mr. Kassam are each Canadian citizens. N IA FI To come Anson Funds Management LP, Anson Management GP LLC, Mr. Moore, Anson Advisors Inc., Mr. Nathoo and Mr. Kassam are the beneficial owners of 176,094 shares of Common Stock held by the Fund. Anson Funds Management LP, Anson Management GP LLC, Mr. Moore, Anson Advisors Inc., Mr. Nathoo and Mr. Kassam are the beneficial owners of 7.4% of the outstanding shares of Common Stock. This percentage is determined by dividing 176,094 by 2,369,552, which is the number of Common Stock issued and outstanding, as reported in the Issuer's Annual Report on Form 10-K/A filed with the Securities and Exchange Commission (the "SEC") on April 30, 2025. See Section 4(a) See Section 4(a) See Section 4(a) See Section 4(a) Y Y Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. By signing below I certify that, to the best of my knowledge and belief, the foreign regulatory scheme applicable to [Name of institutional investor will be inserted here in your proof] is substantially comparable to the regulatory scheme applicable to the functionally equivalent U.S. institution(s). I also undertake to furnish to the Commission staff, upon request, information that would otherwise be disclosed in a Schedule 13D. Anson Funds Management LP /s/ Tony Moore 05/15/2025 Anson Management GP LLC /s/ Tony Moore 05/15/2025 Tony Moore /s/ Tony Moore 05/15/2025 Anson Advisors Inc. /s/ Amin Nathoo 05/15/2025 /s/ Moez Kassam 05/15/2025 Amin Nathoo /s/ Amin Nathoo 05/15/2025 Moez Kassam /s/ Moez Kassam 05/15/2025