144 0001797707 XXXXXXXX LIVE 0001490978 SCHRODINGER INC 001-39206 1540 Broadway, 24th Floor New York NY 10036 2122955800 RAMY SAMIR FARID Director Officer Common Morgan Stanley Smith Barney LLC Executive Financial Services

1 New York Plaza 8th Floor New York NY 10004

86000 1066400.00 64660908 04/16/2026 NASDAQ Common 04/16/2026 Exercise of Stock Options Issuer N 86000 04/16/2026 Cash N RAMY SAMIR FARID

1540 Broadway, 24th Floor New York NY 10036

Common 03/05/2026 3661 47248.87 RAMY SAMIR FARID

1540 Broadway, 24th Floor New York NY 10036

Common 03/02/2026 5560 66151.21 The securities to be sold were and will be received upon the exercise of stock options over the next three months. The dates of acquisition and payment were and will be the dates of exercise/sale. 04/16/2026 09/02/2025 /s/ Ramy Samir Farid