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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Cash flows from operating activities:    
Net loss $ (82,125) $ (35,493)
Adjustments to reconcile net loss to net cash used in operating activities:    
(Gain) loss on equity investments (11,828) 1,781
Noncash revenue from equity investments   (11)
Fair value adjustments 21,864 (19,906)
Depreciation and amortization 2,095 1,614
Stock-based compensation 19,561 11,382
Noncash research and development expenses   811
Noncash investment amortization 1,719 2,343
(Gain) loss on disposal of property and equipment (4) 19
Gain on lease termination (2)  
Decrease (increase) in assets, net of acquisition:    
Accounts receivable, net 13,489 10,064
Unbilled and other receivables (4,095) (925)
Reduction in the carrying amount of right of use assets 3,140 2,663
Prepaid expenses and other assets (8,719) (3,914)
(Decrease) increase in liabilities, net of acquisition:    
Accounts payable (2,938) (2,489)
Accrued payroll, taxes, and benefits (1,872) (1,460)
Deferred revenue (17,887) (8,030)
Lease liabilities 364 (2,816)
Other accrued liabilities 2,860 4,074
Net cash used in operating activities (64,378) (40,293)
Cash flows from investing activities:    
Purchases of property and equipment (3,670) (3,427)
Purchases of equity investments (600) (1,700)
Distribution from equity investment 11,828 375
Proceeds from sale of equity investments   15,735
Acquisition, net of acquired cash (6,427)  
Purchases of marketable securities (111,215) (222,725)
Proceeds from maturity of marketable securities 180,710 164,645
Net cash provided by (used in) investing activities 70,626 (47,097)
Cash flows from financing activities:    
Issuances of common stock upon stock option exercises 1,304 5,268
Contribution by noncontrolling interest   25
Net cash provided by financing activities 1,304 5,293
Net increase (decrease) in cash and cash equivalents and restricted cash 7,552 (82,097)
Cash and cash equivalents and restricted cash, beginning of period 123,267 202,796
Cash and cash equivalents and restricted cash, end of period 130,819 120,699
Supplemental disclosure of cash flow and noncash information    
Cash paid for income taxes 171 224
Supplemental disclosure of non-cash investing and financing activities    
Purchases of property and equipment in accounts payable 80 $ 51
Acquisition of right to use assets, contingency resolution 1,513  
Acquisition of right of use assets 14,767  
Acquisition of lease liabilities $ 14,767