Equity Investments - Additional Information (Details) - USD ($)	1 Months Ended			3 Months Ended
	Jul. 30, 2021	May 31, 2021	May 31, 2020	Mar. 31, 2022	Mar. 31, 2021	Dec. 31, 2021	Dec. 31, 2020
Schedule of Equity Method Investments [Line Items]
Equity investments gains (losses)					$ (1,781,000)
Equity investments				$ 37,002,000		$ 43,167,000
Nimbus Therapeutics, LLC
Schedule of Equity Method Investments [Line Items]
Equity investments gains (losses)				0	0
Equity investments				0		0
Morphic Holding, Inc.
Schedule of Equity Method Investments [Line Items]
Equity investments gains (losses)				(6,037,000)	24,824,000
Equity investments				33,524,000		39,561,000
Ravenna Therapeutics
Schedule of Equity Method Investments [Line Items]
Common shares received in connection with merger			2,676,191
Carrying value of non-marketable equity securities				19,000		19,000
Ajax Therapeutics, Inc
Schedule of Equity Method Investments [Line Items]
Equity investments				1,700,000		$ 1,700,000
Ajax Therapeutics, Inc | Series B Preferred Stock
Schedule of Equity Method Investments [Line Items]
Number of preferred shares purchased		631,377
Cash payments to purchase of shares		$ 1,700,000
ShouTi
Schedule of Equity Method Investments [Line Items]
Equity investments gains (losses)				(128,000)	$ 0
Equity investments				1,759,000			$ 1,887,000
ShouTi | Series B Preferred Stock
Schedule of Equity Method Investments [Line Items]
Number of preferred shares purchased	494,035
Cash payments to purchase of shares	$ 2,000,000
Eonix
Schedule of Equity Method Investments [Line Items]
Equity investments gains (losses)				0
Equity investments				$ 0
Shares received in connection with master services agreement				4,000,000