Revenue Recognition - Additional Information (Details)		3 Months Ended		12 Months Ended
	Nov. 22, 2020 USD ($) Program	Jun. 30, 2021 USD ($)	Jun. 30, 2020 USD ($)	Dec. 31, 2021 USD ($)	Dec. 31, 2020 USD ($)	Dec. 31, 2019 USD ($)
Revenue Remaining Performance Obligation Expected Timing Of Satisfaction [Line Items]
Deferred revenue, revenue recognized				$ 42,127,000	$ 24,921,000
Percentage of revenue expected to be recognized				65.00%
Unsatisfied performance obligation				$ 26,694,000
Agreement with Gates Ventures, LLC
Revenue Remaining Performance Obligation Expected Timing Of Satisfaction [Line Items]
Software contribution revenue related to agreement cover period start date				Jun. 23, 2020
Software contribution revenue related to agreement cover period end date				Jun. 22, 2023
Deferred revenue				$ 0
Agreement with Gates Ventures, LLC | First Anniversary
Revenue Remaining Performance Obligation Expected Timing Of Satisfaction [Line Items]
Software contribution revenue recognition		$ 1,000,000	$ 1,000,000
Agreement with Gates Ventures, LLC | Second Anniversary
Revenue Remaining Performance Obligation Expected Timing Of Satisfaction [Line Items]
Additional revenue entitled to receive				1,000,000
Collaboration and License Agreement | BMS
Revenue Remaining Performance Obligation Expected Timing Of Satisfaction [Line Items]
Upfront fee received	$ 55,000,000
Maximum milestone payments to be received	$ 2,700,000,000
Number of programs under agreement | Program	5
Transaction price	$ 55,000,000
Deferred revenue, revenue recognized				13,749,000	988,000
Deferred revenue				40,263,000	54,012,000
Receivable from collaboration				$ 0
Maximum
Revenue Remaining Performance Obligation Expected Timing Of Satisfaction [Line Items]
Contract with customers, payment terms				60 days
Maximum | Agreement with Gates Ventures, LLC
Revenue Remaining Performance Obligation Expected Timing Of Satisfaction [Line Items]
Software contribution revenue recognition amount				$ 3,000,000
Minimum
Revenue Remaining Performance Obligation Expected Timing Of Satisfaction [Line Items]
Contract with customers, payment terms				30 days
On Premise Software
Revenue Remaining Performance Obligation Expected Timing Of Satisfaction [Line Items]
Revenue, practical expedient, financing component [true false]				true
Drug Discovery Services
Revenue Remaining Performance Obligation Expected Timing Of Satisfaction [Line Items]
Milestone payment yet to be achieved				$ 2,250,000	250,000	$ 1,500,000
Revenue recognized with milestones				2,250,000	$ 85,000	$ 1,500,000
Drug Discovery Contribution
Revenue Remaining Performance Obligation Expected Timing Of Satisfaction [Line Items]
Deferred revenue				$ 1,129,000
Oncology Product | Collaboration and License Agreement | BMS
Revenue Remaining Performance Obligation Expected Timing Of Satisfaction [Line Items]
Maximum milestone payments to be received	585,000,000
Milestone payments to be received upon achievement of certain specified research, development, and regulatory milestones	360,000,000
Milestone payments to be received upon achievement of certain specified commercial milestones	225,000,000
Neurology and Immunology Product | Collaboration and License Agreement | BMS
Revenue Remaining Performance Obligation Expected Timing Of Satisfaction [Line Items]
Maximum milestone payments to be received	482,000,000
Milestone payments to be received upon achievement of certain specified research, development, and regulatory milestones	257,000,000
Milestone payments to be received upon achievement of certain specified commercial milestones	$ 225,000,000