Equity Investments - Additional Information (Details)		1 Months Ended				3 Months Ended		6 Months Ended
	Feb. 07, 2023 $ / shares shares	Apr. 30, 2022 USD ($) shares	Jul. 31, 2021 USD ($) shares	May 31, 2021 USD ($) shares	May 31, 2020 shares	Jun. 30, 2023 USD ($) shares	Jun. 30, 2022 USD ($)	Jun. 30, 2023 USD ($) shares	Jun. 30, 2022 USD ($)	Dec. 31, 2022 USD ($)
Schedule of Equity Method Investments [Line Items]
Equity investments						$ 106,404,000		$ 106,404,000		$ 25,683,000
Gain (loss) on equity investments						0	$ (11,828,000)	(147,322,000)	$ (11,828,000)
Cash payments to purchase of shares								4,125,000	600,000
Nimbus Therapeutics, LLC
Schedule of Equity Method Investments [Line Items]
Equity investments						205,000		205,000		0
Gain (loss) on equity investments						0	0	(147,322,000)	0
Morphic Holding, Inc.
Schedule of Equity Method Investments [Line Items]
Equity investments						47,869,000		47,869,000		22,335,000
Gain (loss) on equity investments						(16,441,000)	15,405,000	(25,533,000)	21,422,000
Ravenna Therapeutics
Schedule of Equity Method Investments [Line Items]
Common shares received in connection with merger (in shares) | shares					2,676,191
Carrying value of non-marketable equity securities						19,000		19,000		19,000
Ajax Therapeutics, Inc
Schedule of Equity Method Investments [Line Items]
Equity investments						1,700,000		1,700,000		1,700,000
Ajax Therapeutics, Inc | Series B Preferred Stock
Schedule of Equity Method Investments [Line Items]
Number of preferred shares purchased (in shares) | shares				631,377
Cash payments to purchase of shares				$ 1,700,000
Structure Therapeutics
Schedule of Equity Method Investments [Line Items]
Equity investments						56,611,000		56,611,000		$ 1,629,000
Gain (loss) on equity investments						$ (24,300,000)	$ 294,000	$ (50,857,000)	$ 421,000
Structure Therapeutics | Series B Preferred Stock
Schedule of Equity Method Investments [Line Items]
Number of preferred shares purchased (in shares) | shares		148,210	494,035
Cash payments to purchase of shares		$ 600,000	$ 2,000,000
Structure Therapeutics | Common stock
Schedule of Equity Method Investments [Line Items]
Shares owned (in shares) | shares						3,260,495		3,260,495
Structure Therapeutics | ADR
Schedule of Equity Method Investments [Line Items]
Number of shares purchased | shares	275,000
Purchase price (in USD per share) | $ / shares	$ 15
Stock split, conversion ratio	3