X0306 4 2020-02-10 0 0001490978 Schrodinger, Inc. SDGR 0001166559 BILL & MELINDA GATES FOUNDATION TRUST 2365 CARILLON POINT KIRKLAND WA 98033 0 0 1 0 Common stock 2020-02-10 4 C 0 6393429 A 6393429 D Common stock 2020-02-10 4 P 0 588235 17.00 A 6981664 D Series B preferred stock 2020-02-10 4 C 0 29468101 D Common stock 3942041 0 D Series C preferred stock 2020-02-10 4 C 0 47242235 D Common stock 6319743 0 D Series D preferred stock 2020-02-10 4 C 0 35946010 D Common stock 4808612 0 D Series E preferred stock 2020-02-10 4 C 0 33543539 D Common stock 4487226 0 D Limited common stock 2020-02-10 4 C 0 13164193 A Common stock 13164193 13164193 D Upon closing of the Issuer's initial public offering ("IPO"), all of the Series E preferred stock held by Bill & Melinda Gates Foundation Trust (the "Trust") converted automatically into the Issuer's common stock on a 7.47534-for-1 basis without payment of further consideration. There was no expiration date for the Series E preferred stock. Represents shares acquired pursuant to an Issuer directed allocation in connection with the Issuer's IPO of common stock. Upon closing of the Issuer's IPO, the Trust voluntarily exchanged all of its Series B preferred stock and Series C preferred stock into the Issuer's limited common stock on a 7.47534-for-1 basis without payment of further consideration. There was no expiration date for the Series B preferred stock or Series C preferred stock. Upon closing of the Issuer's IPO, (i) 14,249,523 shares of Series D preferred stock converted automatically into the Issuer's common stock on a 7.47534-for-1 basis without payment of further consideration and (ii) 21,696,487 shares of Seried D preferred stock were voluntarily exchanged at the discretion of the Trust into the Issuer's limited common stock on a 7.47534-for-1 basis without further consideration. There was no expiration date for the Series D preferred stock. All shares of the Issuer's limited common stock have no expiration date and may be exchanged at the Trust's election into the Issuer's common stock on a 1-for-1 basis without payment of further consideration. Bill & Melinda Gates Foundation Trust By: /s/ Alan Heuberger, Attorney-in-fact for each of the Co-Trustees, William H. Gates III and Melinda French Gates 2020-02-12