X0508 4/A 2024-05-30 2024-06-03 0001971543 Mural Oncology plc MURA 0001490216 Cuss Francis M C/O MURAL ONCOLOGY PLC 10 EARLSFORT TERRACE DUBLIN 2 L2 D02 T380 IRELAND true false false false false Stock Option (right to buy) 3.35 2024-05-30 4 A false 8462 0.00 A 2034-05-29 Ordinary Shares 8462 8462 D This option was granted on May 30, 2024. This option will vest in full upon the earlier of (i) the first anniversary of the date of the grant or (ii) the date of the next Annual Meeting, subject to the reporting person's continued service with the Issuer. This amendment to Form 4 is being filed solely to correct the price of the derivative security, which was previously reported as being $3.35 due to a scrivener's error. /s/ Maiken Keson-Brookes, attorney-in-fact for Francis M. Cuss 2024-06-05