X0306 4 2019-10-07 0001781983 Aprea Therapeutics, Inc. APRE 0001488771 Christenson Johan 535 BOYLSTON STREET BOSTON MA 02116 true Common Stock 2019-10-07 4 C 0 1661382 A 1671941 I See footnote Common Stock 2019-10-07 4 C 0 427496 A 2099437 I See footnote Common Stock 2019-10-07 4 P 0 266667 15 A 2366104 I See footnote Series B Convertible Preferred Stock 2019-10-07 4 C 0 1661382 D Common Stock 1661382 0 I See footnote Series C Convertible Preferred Stock 2019-10-07 4 C 0 427496 D Common Stock 427496 0 I See footnote These shares of Series B Convertible Preferred Stock and Series C Convertible Preferred Stock (collectively, "Preferred Stock") automatically converted into shares of the Issuer's Common Stock ("Shares"), on a 1-for-1 basis, immediately prior to the completion of the Issuer's initial public offering. The Preferred Stock had no expiration date. These Shares and Preferred Stock are held directly by HealthCap VII, L.P. ("HCLP"). HealthCap VII GP SA ("HCSA") is the sole general partner of HCLP and has voting and investment control over the Shares and Preferred Stock held by HCLP. The reporting person has an indirect interest in HCSA and is an employee of HealthCap VII Advisor AB. The reporting person disclaims beneficial ownership of Shares and Preferred Stock held by HCLP except to the extent of any pecuniary interest therein. /s/ Scott M. Coiante, attorney-in-fact 2019-10-07