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Debt - Additional Information (Detail) - Roche Credit Facility [Member] - USD ($)
3 Months Ended 6 Months Ended
Jul. 31, 2017
Aug. 02, 2016
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Line Of Credit Facility [Line Items]            
Credit facility, borrowing capacity $ 200,000,000 $ 100,000,000        
Credit facility, available borrowing capacity $ 80,000,000          
Credit facility, quarterly commitment fee percentage on available balance, payable during draw period 0.40% 0.30%        
Credit facility, draw period 4 years 3 years        
Credit facility, interest rate 6.50% 5.00%        
Credit facility, payments description         The Company shall pay Roche quarterly during the Draw Period and for six months thereafter accrued interest on the outstanding principal of the loans. Beginning six months after the Draw Period and for five years thereafter, the Company shall pay Roche quarterly equal payments of principal, with accrued interest, in arrears until maturity of the Roche Credit Facility on February 2, 2026 (the “Final Maturity Date”).  
Credit facility, frequency of periodic payment         quarterly  
Credit facility, maturity date Feb. 02, 2026          
Credit facility, covenants description         The Roche Credit Facility contains certain affirmative covenants, including, among others, obligations for the Company to provide monthly and annual financial statements, to meet specified minimum cash requirements, to provide tax gross-up and indemnification protection, and to comply with laws. The Roche Credit Facility also contains certain negative covenants, including, among others, restrictions on the Company’s ability to dispose of certain assets, to acquire another company or business, to encumber or permit liens on certain assets, to incur additional indebtedness (subject to customary exceptions), and to pay dividends on the Company’s common stock. The Company was in compliance with its covenants under the Roche Credit Facility as of June 30, 2018.  
Debt default, short-term debt, amount     $ 0   $ 0  
Credit facility, borrowings outstanding     110,000,000   110,000,000  
Credit facility, remaining borrowing capacity     90,000,000   90,000,000  
Interest expense     $ 1,700,000 $ 100,000 $ 2,900,000 $ 200,000
Foreign Subsidiaries [Member]            
Line Of Credit Facility [Line Items]            
Equity interest percentage held   65.00%        
Achievement of Certain Milestones [Member]            
Line Of Credit Facility [Line Items]            
Credit facility, available borrowing capacity $ 120,000,000