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Net Loss Per Common Share - Potential Common Stock Equivalents Excluded from Calculation of Diluted Net Loss Per Common Share (Detail) - shares
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Total 2,564,383 2,654,541 3,127,954
Outstanding Stock Options [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Total 1,267,329 1,684,783 2,792,021
Unvested Restricted Stock [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Total 1,297,054 969,758 335,933