Property and Equipment

12 Months Ended

Dec. 31, 2016

Property Plant And Equipment [Abstract]

Property and Equipment

5. Property and Equipment

Property and equipment and related accumulated depreciation and amortization are as follows (in thousands):

	December 31,
	2016			2015
Lab equipment	$	34,727		$	27,883
Computer equipment		11,534			10,542
Software		5,429			3,703
Furniture and office equipment		3,638			3,376
Leasehold improvements		24,730			18,677
Construction in process		4,512			5,172
		84,570			69,353
Less accumulated depreciation and amortization		(43,084	)		(28,020	)
	$	41,486		$	41,333

Depreciation and amortization expense for the years ended December 31, 2016, 2015, and 2014 was $15,949,000, $10,600,000, and $8,195,000, respectively. The Company classifies capitalized internal-use software in lab equipment, computer equipment and software based on its intended use. Depreciation expense related to all capitalized internal-use software for the years ended December 31, 2016, 2015, and 2014 was $213,000, $238,000 and $459,000, respectively. The remaining unamortized capitalized internal-use software costs at December 31, 2016 and 2015 were $1,052,000 and $0, respectively.