X0306 4 2017-07-13 0 0001488613 Foundation Medicine, Inc. FMI 0001585017 Ryan Jason 150 SECOND STREET C/O FOUNDATION MEDICINE, INC. CAMBRIDGE MA 02141 0 1 0 0 Chief Financial Officer Common Stock 2017-07-13 4 S 0 5084 39.77 D 66638 D The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 26, 2016. The sale of a portion of these shares were effected to cover tax liabilities of the reporting person in connection with the vesting and release of restricted stock units. The price reported in this Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $39.30 to $40.00, inclusive. The reporting person undertakes to provide the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each price within the ranges set forth in this footnote. /s/ Robert W. Hesslein, as Attorney-in-Fact for Jason Ryan 2017-07-17