X0306 4 2016-10-20 0 0001488613 Foundation Medicine, Inc. FMI 0001585017 Ryan Jason 150 SECOND STREET C/O FOUNDATION MEDICINE, INC. CAMBRIDGE MA 02141 0 1 0 0 Chief Financial Officer Common Stock 2016-10-20 4 S 0 506 22.45 D 59422 D The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 26, 2016. The sale of these shares were effected to cover tax liabilities of the reporting person in connection with the vesting and release of restricted stock units. /s/ Robert W. Hesslein, as Attorney-in-Fact for Jason Ryan 2016-10-24