X0306 4 2016-08-19 0 0001488613 Foundation Medicine, Inc. FMI 0001585017 Ryan Jason 150 SECOND STREET C/O FOUNDATION MEDICINE, INC. CAMBRIDGE MA 02141 0 1 0 0 Chief Financial Officer Common Stock 2016-08-19 4 S 0 8863 23.91 D 61148 D Common Stock 2016-08-19 4 M 0 5000 7.12 A 66148 D Common Stock 2016-08-19 4 S 0 5000 23.94 D 61148 D stock option (right to buy) 7.12 2016-08-19 4 M 0 5000 0.00 A 2023-05-21 common stock 5000 15250 D The price reported in this Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $23.59 to $24.11, inclusive. The reporting person undertakes to provide the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each price within the ranges set forth in this footnote. The price reported in this Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $23.58 to $24.15, inclusive. The reporting person undertakes to provide the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each price within the ranges set forth in this footnote. This option was granted on May 21, 2013 and vests in equal quarterly installments over a four-year period beginning on April 1, 2014. /s/ Robert W. Hesslein, as Attorney-in-Fact for Jason Ryan 2016-08-23