X0306 4 2015-04-07 0 0001488613 Foundation Medicine, Inc. FMI 0001585018 Hesslein Robert W. 150 SECOND STREET C/O FOUNDATION MEDICINE, INC. CAMBRIDGE MA 02141 0 1 0 0 SVP and General Counsel Common Stock 2015-04-07 4 U 0 35020 50.00 D 33105 D The amount reported represents the estimated number of shares sold by the reporting person in connection with the tender offer for shares of Common Stock of the Issuer (the "Tender Offer") by Roche Holdings, Inc. ("Roche"). Roche will purchase only a prorated portion of the shares properly tendered by each tendering stockholder. Based on a preliminary count reported by Roche, the preliminary proration factor for the Tender Offer is approximately 80.7%. If necessary, an amended Form 4 will be filed to report the number of shares actually sold by the reporting person in connection with the Tender Offer once the final proration factor is determined. /s/ Robert W. Hesslein 2015-04-09