Note 1 - Nature of Operations	12 Months Ended
Dec. 31, 2022
Notes to Financial Statements
Nature of Operations [Text Block]	NOTE 1: NATURE OF OPERATIONS Atossa Therapeutics, Inc. (the Company) was incorporated on April 30, 2009, in the State of Delaware to develop and market medical devices, laboratory tests and therapeutics to address breast health conditions. The Company is currently focused on developing proprietary innovative medicines in areas of significant unmet medical need in oncology, with a current focus on breast cancer and other breast conditions. The Company's fiscal year ends on December 31. *Impact of the Ongoing Coronavirus Pandemic* The ongoing COVID-19 pandemic may affect the Company’s operations and those of third-parties on which the Company relies, including causing possible disruptions in the supply of the Company’s (Z)-endoxifen, AT-H201 and the pace of enrollment in the Company’s clinical trials. In addition, the COVID-19 pandemic may affect the operations of the U.S. FDA and other health authorities, including similar entities/agencies in Sweden and Australia, which could result in delays in meetings, reviews and approvals. As the COVID-19 pandemic reaches endemic stages, the extent to which it may continue to impact the Company’s operations, including COVID-19-related delays or other impacts on the Company’s business, financing or clinical trial activities or on healthcare systems or the global economy as a whole, remains highly uncertain and difficult to predict; however, the Company has not experienced a significant delay in the enrollment or the drug supply for its ongoing and planned clinical studies, including studies of (Z)-endoxifen and AT-H201.

Note 1 - Nature of Operations

12 Months Ended

Dec. 31, 2022

Atossa Therapeutics, Inc. (the Company) was incorporated on April 30, 2009, in the State of Delaware to develop and market medical devices, laboratory tests and therapeutics to address breast health conditions. The Company is currently focused on developing proprietary innovative medicines in areas of significant unmet medical need in oncology, with a current focus on breast cancer and other breast conditions. The Company's fiscal year ends on December 31.

Impact of the Ongoing Coronavirus Pandemic

The ongoing COVID-19 pandemic may affect the Company’s operations and those of third-parties on which the Company relies, including causing possible disruptions in the supply of the Company’s (Z)-endoxifen, AT-H201 and the pace of enrollment in the Company’s clinical trials. In addition, the COVID-19 pandemic may affect the operations of the U.S. FDA and other health authorities, including similar entities/agencies in Sweden and Australia, which could result in delays in meetings, reviews and approvals. As the COVID-19 pandemic reaches endemic stages, the extent to which it may continue to impact the Company’s operations, including COVID-19-related delays or other impacts on the Company’s business, financing or clinical trial activities or on healthcare systems or the global economy as a whole, remains highly uncertain and difficult to predict; however, the Company has not experienced a significant delay in the enrollment or the drug supply for its ongoing and planned clinical studies, including studies of (Z)-endoxifen and AT-H201.