Note 14 - Stock Based Compensation (Tables)

3 Months Ended

Mar. 31, 2022

Notes Tables

Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]

	Three Months Ended March 31,
	2022
Risk-free interest rate		1.86% - 2.53%
Expected term (in years)		5.51 - 6.11
Dividend yield		-
Expected volatility		117% - 128%

Share-Based Payment Arrangement, Option, Activity [Table Text Block]

	Number of Underlying Shares		Weighted- Average Exercise Price Per Share		Weighted- Average Contractual Life Remaining in Years		Aggregate Intrinsic Value
Outstanding as of January 1, 2022		10,027	$	2.82			$	1,006
Granted		2,722		1.25
Exercised		-		-
Forfeited		-		-
Expired		-		-
Outstanding as of March 31, 2022		12,749		2.48		8.42	$	-
Exercisable as of March 31, 2022		7,279		2.82		7.67
Vested and expected to vest		12,749	$	2.48		8.42	$	-

Share-Based Payment Arrangement, Option [Member]

Notes Tables

Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]

	Three Months Ended March 31,
	2022		2021
General and administrative	$	1,184	$	450
Research and development		622		190
Total stock compensation expense	$	1,806	$	640