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Note 10 - Net Loss Per Share (Tables)
9 Months Ended
Sep. 30, 2021
Notes Tables  
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
   

Three Months Ended September 30,

   

Nine Months Ended September 30,

 
   

2021

   

2020

   

2021

   

2020

 

Numerator

                               

Net loss attributable to common shareholders

  $ (5,197,145 )   $ (3,491,071 )   $ (15,774,462 )   $ (10,344,633 )

Denominator

                               

Weighted average common shares outstanding used to compute net loss per share, basic and diluted

    126,537,544       10,162,770       113,689,961       9,496,222  

Net loss per share of common stock, basic and diluted:

  $ (0.04 )   $ (0.34 )   $ (0.14 )   $ (1.09 )
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
   

Three Months Ended September 30,

   

Nine Months Ended September 30,

 
   

2021

   

2020

   

2021

   

2020

 

Options to purchase common stock

    10,043,575       7,158,387       8,682,997       5,825,082  

Series B convertible preferred stock

    166,142       177,562       172,909       183,544  

Warrants to purchase common stock

    22,356,105       1,070,028       24,773,777       1,070,028  
      32,565,822       8,405,977       33,629,683       7,078,654