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Note 9 - Net Loss Per Share (Tables)
3 Months Ended
Mar. 31, 2020
Notes Tables  
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
   
Three Months Ended March 31,
 
   
2020
   
2019
 
Numerator
 
 
 
 
 
 
 
 
Net loss attributable to common shareholders
  $
(2,947,420
)   $
(4,073,307
)
Denominator
 
 
 
 
 
 
 
 
Weighted average common shares outstanding used to compute net loss per share, basic and diluted
   
9,130,984
     
6,565,514
 
Net loss per share of common stock, basic and diluted:
  $
(0.32
)   $
(0.62
)
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
   
Three Months Ended March 31,
 
   
2020
   
2019
 
Options to purchase common stock
   
4,308,383
     
783,383
 
Series B convertible preferred stock
   
190,617
     
458,994
 
Warrants to purchase common stock
   
1,070,028
     
3,369,468
 
     
5,569,028
     
4,611,845