Note 14 - Stock Based Compensation - Stock-based Compensation Expense (Details) - USD ($)		12 Months Ended
	Jan. 13, 2019	Dec. 31, 2019	Dec. 31, 2018
Stock compensation expense		$ 7,102,119	$ 1,053,496
Liability Options [Member]
Stock compensation expense	$ 1,741,919		1,410,025
General and Administrative Expense [Member]
Stock compensation expense		4,656,963	809,110
General and Administrative Expense [Member] | Liability Options [Member]
Stock compensation expense	1,074,183		869,515
Research and Development Expense [Member]
Stock compensation expense		$ 2,445,156	244,386
Research and Development Expense [Member] | Liability Options [Member]
Stock compensation expense	$ 667,736		$ 540,510