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STOCKHOLDERS' EQUITY (Tables)
6 Months Ended
Jun. 30, 2016
Stockholders' Equity Note [Abstract]  
Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block]
As of June 30, 2016, warrants to purchase 6,033,426 shares of common stock were outstanding including:
 
 
 
Outstanding
Warrants to
Purchase Shares
 
Exercise Price
 
Expiration Date
 
 
 
 
 
 
 
 
 
2011 private placement
 
 
4,252,050
 
 
$1.25 - 1.60
 
May 18, 2018
Acueity warrants
 
 
325,000
 
 
5.00
 
September 30, 2017
2014 public offering
 
 
1,166,849
 
 
3.00
 
January 29, 2019
Placement agent fees for Company’s offerings
 
 
242,027
 
 
2.12 – 12.43
 
March - November, 2018
Outside consulting
 
 
47,500
 
$
4.24
 
January 14, 2018
 
 
 
6,033,426