RELATED PARTY TRANSACTIONS (Tables)

3 Months Ended

Mar. 31, 2013

Related Party Transactions [Abstract]

Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]

The Company estimated the fair value of these options using the Black-Scholes-Merton option pricing model based on the following weighted-average assumptions:

							Employees &			Non-employee			Non-employee
	CEO & CSO			Dr. Hunkapiller			Officers			Directors			Directors			Employees			Employees
Date of grant		22-Jul-10			4-Apr-11			1-Sep-11			1-Sep-11			30-Apr-12			17-Dec-12			20-Dec-12
Fair value of common stock on date of grant	$	2.7560	(B)	$	0.9060	(C)	$	0.9060	(C)	$	0.9060	(C)	$	6.00	(D)	$	4.24	(E)	$	4.11	(E)
Exercise price of the options	$	5.00		$	1.25		$	1.25		$	1.25		$	6.00		$	4.24		$	4.11
Expected life of the options (years)		3.33			5.31			5.65			5.65			5.00			5.74-6.10			6.11
Dividend yield		0.00	%		0.00	%		0.00	%		0.00	%		0.00	%		0.00	%		0.00	%
Expected volatility		58.59	%		54.12	%		53.90	%		53.90	%		62.46	%		42.44-44.58	%		42.44	%
Risk-free interest rate		1.03	%		2.26	%		1.08	%		1.08	%		0.89	%		0.91-0.99	%		0.99	%
Expected forfeiture per year (%)		0.00	%		0.00	%			(A)		0.00	%		0.00	%		0.00-10.00	%		0.00	%
Weighted-average fair value of the options (per unit)	$	0.6744		$	0.3729		$	0.3579		$	0.3579		$	3.0367			$1.7426-1.7887		$	1.7842

	Employee			Employees &			Employee			CEO & CSO
				Officers
Date of grant		3-Jan-13			4-Jan-13			5-Jan-13			11-Mar-13
Fair value of common stock on date of grant	$	4.31	(E)	$	4.11	(E)	$	3.95	(E)	$	6.57	(E)
Exercise price of the options	$	4.31		$	4.11		$	3.95		$	6.57
Expected life of the options (years)		6.11			6.11			6.11			5.00
Dividend yield		0.00	%		0.00	%		0.00	%		0.00	%
Expected volatility		42.23	%		43.79	%		42.22	%		47.09	%
Risk-free interest rate		0.99	%		0.99	%		1.13	%		0.90-1.13	%
Expected forfeiture per year (%)		10.00	%		10.00	%		10.00			0	%
Weighted-average fair value of the options (per unit)		$ 1.6970	%		$ 1.6922			$ 1.3511			$ 2.7022

(A) 0.00% for the first year after the grant date, and 96.35% for every three months thereafter.

(B) The fair value of the Company's common stock was derived implicitly from the public offering filed in March 2010 at $3.00 per share and from the terms of an underwritten offering contemplated in July 2010 at $6.00 per Unit that was filed in October 2010, with $2.756 per share being allocated to common stock using an iterative approach in order for the combined fair value of the common stock and warrants to equal the amount of consideration to be received for the offering.

(C) The fair value of the Company's common stock was derived implicitly from the Private Placement during April through June 2011 at $1.25 per Unit, wherein one Unit was comprised of one share of common stock and one warrant to purchase one share of common stock at an exercise price of $1.60 per share.

(D)	The fair value of the Company's common stock was derived implicitly from the public offering filed in February 2012 at $6.00 per share.
(E)	The fair values of the Company's common stock were derived from the closing prices on the NASDAQ Capital Market as of the dates of grant.

Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block]

Options issued and outstanding as of March 31, 2013 and their activities during the three months then ended are as follows:

	Number of Underlying Shares			Weighted-Average Exercise Price Per Share		Weighted-Average Contractual Life Remaining in Years
Outstanding as of January 1, 2013		1,051,636		$	3.78
Granted		602,710			4.41
Expired		-			-
Forfeited		(2,667	)		1.25
Exercised		(1,380	)		1.25
Outstanding as of March 31, 2013		1,650,299			4.01		7.94
Exercisable as of March 31, 2013		624,508			3.72		5.81
Vested and expected to vest (1)		1,641,050			4.01		7.92

(1) Includes vested shares and unvested shares after a forfeiture rate is applied.

Schedule of Share-based Compensation Arrangement by Share-based Payment Award Non-Vested Shares [Table Text Block]

A summary of the status of the Company’s unvested shares as of March 31, 2013 and changes during the three month period then ended is presented below:

Unvested Shares	Shares			Weighted-Average Grant-Date Fair Value
Unvested as of January 1, 2013		520,541		$	823,652
Granted		602,710			1,088,350
Vested		(94,335	)		(218,144	)
Forfeited		(2,667	)		(955	)
Unvested as of March 31, 2013		1,026,249		$	1,692,904