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Loan payable Outstanding Debt (Tables)
12 Months Ended
Dec. 31, 2018
Debt Disclosure [Abstract]  
Schedule of Long-term Debt Instruments [Table Text Block]
 
 
December 31,
 
 
2018
 
2017
Term Loans
 
 
 
 
Term Loan A - 6.9% principal
 
$
7,619

 
$
10,000

Term Loan B - 6.9% principal
 
7,619

 
10,000

Term Loan C - 7.4% principal
 
12,000

 
15,000

Term Loan D - 8.8% principal
 
663

 

Term Loan E - 8.8% principal
 
7,098

 

Final fee obligation
 
3,288

 
2,429

Repayment of principal
 

 
(7,762
)
Unamortized issuance costs
 
(2,245
)
 
(1,641
)
Total debt, net
 
36,042

 
28,026

Current portion of long-term debt
 

 
(7,927
)
Long-term debt
 
$
36,042

 
$
20,099