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Summary of significant accounting policies (Tables)
12 Months Ended
Dec. 31, 2018
Accounting Policies [Abstract]  
Schedule of Accounts, Notes, Loans and Financing Receivable
The allowance for doubtful accounts as of December 31, 2018 and 2017, comprised the following (in thousands):
 
Allowance for doubtful accounts
Balance at December 31, 2016
$
2,740

Provision for doubtful accounts
14

Balance at December 31, 2017
$
2,754

Provision for doubtful accounts
23

Write off of uncollectible accounts
(2,702
)
Balance at December 31, 2018
$
75

Estimated Useful Lives of Property and Equipment
Property, equipment and leasehold improvements are recorded at cost and depreciated using the straight-line method over the estimated useful lives of the assets, which are:

Plant and Machinery
3 – 5 years
Instruments
4 – 5 years
Office equipment
3 – 7 years
Leasehold improvements
over the shorter of the remaining life of the lease or the useful economic life of the asset
Schedule of Product Warranty Liability
Product warranty reserve activity for the years ended December 31, 2018, 2017 and 2016 is as follows (in thousands):

 
2018
 
2017
 
2016
Beginning balance
$
470

 
$
219

 
$
118

Warranty expenses incurred
(1,495
)
 
(1,160
)
 
(421
)
Provisions
1,355

 
1,411

 
522

Ending balance
$
330

 
$
470

 
$
219

Schedule of Weighted Average Number of Shares

The calculations of diluted net loss per share for the years ended December 31, 2018, 2017 and 2016 did not include the effects of the following stock options or other unvested equity awards which were outstanding as of the end of each year because the inclusion of these securities would have been anti-dilutive (in thousands).
 
 
Year Ended December 31,
 
2018
 
2017
 
2016
Options outstanding to purchase common stock
2,440

 
2,490

 
2,570

Other unvested equity awards
2,994

 
2,307

 
2,000

Total
5,434

 
4,797

 
4,570

Schedules of Concentration of Risk, by Risk Factor
The following table summarizes customers who accounted for 10% or more of net accounts receivable:
 
 December 31,
 
2018
 
2017
Laboratory Corporation of America, Inc.
24
%
 
23
%